Evidence map›Paper›PMID 39104637›Full record

ArticleSkin health and disease2024

Association of frequent intake of trans fatty acids and saturated fatty acids in diets with increased susceptibility of atopic dermatitis exacerbation in young Chinese adults: A cross-sectional study in Singapore/Malaysia.

Jun Jie Lim, Sing Wei Lim, Kavita Reginald, Yee-How Say, Mei Hui Liu, Fook Tim Chew

Abstract read
In one paragraph

Article in Skin health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Healthy Diet Intervention for Treating Atopic Dermatitis: A Pilot Randomised Controlled Trial.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jun Jie LimDepartment of Biological Sciences Faculty of Science National University of Singapore Singapore Singapore.ORCID https://orcid.org/0000-0001-5485-1749
Sing Wei LimDepartment of Biological Sciences Faculty of Science National University of Singapore Singapore Singapore.
Kavita ReginaldDepartment of Biological Sciences Faculty of Science National University of Singapore Singapore Singapore.ORCID https://orcid.org/0000-0003-1530-5934
Yee-How SayDepartment of Biological Sciences Faculty of Science National University of Singapore Singapore Singapore.ORCID https://orcid.org/0000-0003-2363-5239
Mei Hui LiuDepartment of Food Science & Technology Faculty of Science National University of Singapore Singapore Singapore.ORCID https://orcid.org/0000-0001-7405-7008
Fook Tim ChewDepartment of Biological Sciences Faculty of Science National University of Singapore Singapore Singapore.ORCID https://orcid.org/0000-0003-1337-5146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & Objective: Numerous evidence has attributed diets with a high fatty acids (FAs) intake to be associated with atopic dermatitis (AD) development. Therefore, this study investigated the association between intake frequencies of five dietary FAs and AD exacerbations among young Chinese adults from Singapore and Malaysia. Methods: A validated International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire was investigator-administered to 13,561 subjects to collect information on socioeconomic, anthropometric, dietary and lifestyles habits, and personal/family medical histories. Six novel dietary indices were derived to analyse the associations between total FAs, trans fatty acids (TFAs), saturated fatty acids (SFAs), monounsaturated fatty acids, linoleic acids, and alpha-linolenic acids in diets and AD exacerbation. Synergy factor (SF) analysis was used to identify interactions between the dietary FAs to influence disease susceptibility. Results: In our multivariable model adjusted for age, gender, BMI, parental eczema, and lifestyle factors, a diet high in total estimated FAs was strongly associated with AD (Adjusted Odds Ratio (AOR): 1.227; 95% Confidence Interval (CI): 1.054-1.429; adjusted Conclusion: Overall, these results highlighted an association between high dietary TFAs and SFAs and AD exacerbations in an Asian population.

Identifiers

PMID39104637
PMCPMC11297457

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.