Evidence map›Paper›PMID 39104039›Full record

ArticleJournal of gastroenterology and hepatology2024

Hepatitis B clinical care provision in pregnancy: A whole-of-population linkage study in Victoria, Australia.

Jennifer H MacLachlan, Nicole Romero, Nicole Allard, Stacey L Rowe, Benjamin C Cowie

Abstract read
In one paragraph

Article in Journal of gastroenterology and hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer H MacLachlanWHO Collaborating Centre for Viral Hepatitis, The Doherty Institute, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-7654-4536
Nicole RomeroWHO Collaborating Centre for Viral Hepatitis, The Doherty Institute, Melbourne, Victoria, Australia.
Nicole AllardWHO Collaborating Centre for Viral Hepatitis, The Doherty Institute, Melbourne, Victoria, Australia.
Stacey L RoweSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Benjamin C CowieWHO Collaborating Centre for Viral Hepatitis, The Doherty Institute, Melbourne, Victoria, Australia.

Funding

Royal Melbourne Hospital Foundation Research Project Grant PG-014-2016
6 · The paper itself

Abstract

BACKGROUND AND

aimPregnancy is a key setting for engagement in chronic hepatitis B (CHB) care, due to the implications for transmission to the infant and antenatal diagnosis representing an opportunity for ongoing follow-up. This study aimed to identify the coverage and predictors of clinical care for women with CHB during and after pregnancy in a population-level cohort.

methodsNotified CHB cases in Victoria, Australia, were linked with hospitalizations, medical services, and prescribing data, covering the period 1991-2018. Women with an admission for a live birth were identified and services provided during pregnancy were assessed, including general practitioner (GP) or specialist visits, viral load and serology testing, and antiviral treatment. Viral load and serology testing coverage ware also assessed for the 2-year period following pregnancy. Demographic and clinical predictors of viral load testing during pregnancy were assessed.

resultsA total of 11 015 birth events occurred for 6090 women with CHB. During pregnancy most had a GP consultation (91.6%); however, only 39.5% had viral load testing and 41.4% had a gastroenterology or infectious diseases specialist consultation. Viral load testing and serology testing in the 2 years after pregnancy occurred in approximately half (47.9% and 52.2%, respectively) with increases over time. Viral load testing was more likely in those born overseas, those with more than one previous birth, and those living in Melbourne.

conclusionsDespite improvements over time, key gaps were identified in the provision of CHB clinical care during and after pregnancy, with implications for ongoing transmission and adverse outcomes.

Indexed as

Hepatitis B, ChronicPregnancy Complications, InfectiousViral LoadAdultAntiviral AgentsCohort StudiesFemaleHumansInfectious Disease Transmission, VerticalPregnancyVictoriaYoung AdultAntiviral Agentsepidemiologyhepatitis Bpregnancypublic health

Identifiers

PMID39104039
PMCPMC11618317

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.