ArticleBMC public health2024
Loneliness and social isolation are associated with an increased risk of glaucoma: a UK Biobank cohort study.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Association of baseline brain care score with the incidence of age-related eye diseases.Eye (London, England) · 2026Article
- Social isolation and loneliness associate with early menopause and mortality in women: a UK Biobank cohort study.BMC medicine · 2026Article
- Associations between the Mediterranean lifestyle and incident age-related eye diseases: a longitudinal analysis from the UK Biobank.Journal of global health · 2026Article
- Association of loneliness and social isolation with excess risk of cardiovascular events in people with obesity: a prospective cohort study.Journal of global health · 2025Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundLoneliness and social isolation have been found to be associated with various health-related outcomes. Our study aimed to evaluate the association of loneliness and social isolation with the risk of glaucoma.
methodsA total of 373,330 participants from the UK Biobank without glaucoma at recruitment were included in this study. Self-reported questionnaires were used to define loneliness and social isolation. Incident glaucoma events were identified by hospital inpatient admissions and self-reported data. COX proportional hazards models adjusted for sociodemographic, lifestyle, and health-related factors were used to estimate hazard ratios (HRs) and 95% CIs.
resultsDuring a median follow-up of 13.1 (interquartile range: 12.3-13.9) years, 6,489 participants developed glaucoma. After adjusting for confounding factors, loneliness (yes vs. no: adjusted HR: 1.16; 95% CI: 1.04-1.30; P = 0.009) and social isolation (yes vs. no: adjusted HR: 1.08; 95% CI: 1.01-1.16; P = 0.033) were associated with an increased risk of glaucoma.
conclusionsIn this population-based prospective cohort study, loneliness and social isolation were associated with a higher risk of glaucoma.
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