Evidence map›Paper›PMID 39103737›Full record

ArticleAnnals of biomedical engineering2024

Analysis of Energy and Pressure in the Sinus with Different Blood Pressures after Bioprosthetic Aortic Valve Replacement.

Brennan Vogl, Agata Sularz, Sunyoung Ahn, Rajat Gadhave, Scott Lilly, Vinod Thourani, Brian Lindman, Mohamad Alkhouli, Hoda Hatoum

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of biomedical engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brennan VoglDepartment of Biomedical Engineering, Michigan Technological University, 1400 Townsend Dr, Houghton, MI, 49931, USA.
Agata SularzDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Sunyoung AhnDepartment of Biomedical Engineering, Michigan Technological University, 1400 Townsend Dr, Houghton, MI, 49931, USA.
Rajat GadhaveDepartment of Biomedical Engineering, Michigan Technological University, 1400 Townsend Dr, Houghton, MI, 49931, USA.
Scott LillyDepartment of Cardiovascular Medicine, The Ohio State University, Columbus, OH, USA.
Vinod ThouraniDepartment of Cardiovascular Surgery, Piedmont Heart Institute, Marcus Valve Center, Atlanta, GA, USA.
Brian LindmanDivision of Cardiovascular Medicine, Structural Heart and Valve Center, Vanderbilt University Medical Center, Nashville, TN, USA.
Mohamad AlkhouliDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Hoda HatoumDepartment of Biomedical Engineering, Michigan Technological University, 1400 Townsend Dr, Houghton, MI, 49931, USA. hhatoum@mtu.edu.ORCID http://orcid.org/0000-0001-5538-8960

Funding

National Science Foundation 2301649
6 · The paper itself

Abstract

purposeTo investigate the effect of changing systolic and diastolic blood pressures (SBP and DBP, respectively) on sinus flow and valvular and epicardial coronary flow dynamics after TAVR and SAVR.

methodsSAPIEN 3 and Magna valves were deployed in an idealized aortic root model as part of a pulse duplicating left heart flow loop simulator. Different combinations of SBP and DBP were applied to the test setup and the resulting change in total coronary flow from baseline (120/60 mmHg), effective orifice area (EOA), and left ventricular (LV) workload, with each combination, was assessed. In addition, particle image velocimetry was used to assess the Laplacian of pressure (

resultsThis study shows that under an elevated SBP, there is an increase in the total coronary flow, EOA, LV workload, peak velocities downstream of the valve,

conclusionsBlood pressure alters the hemodynamics in the sinus and downstream flow following aortic valve replacement, potentially influencing outcomes in some patients.

Indexed as

Aortic ValveBlood PressureHeart Valve ProsthesisModels, CardiovascularBioprosthesisBlood Flow VelocityCoronary CirculationHeart Valve Prosthesis ImplantationHumansCoronary flowHypertensionParticle image velocimetrySurgical aortic valve replacementTranscatheter aortic valve replacement

Identifiers

PMID39103737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.