Evidence map›Paper›PMID 39103650›Full record

ArticleNature genetics2024

Genetic risk factors for COVID-19 and influenza are largely distinct.

Jack A Kosmicki, Anthony Marcketta, Deepika Sharma, Silvio Alessandro Di Gioia, Samantha Batista, Xiao-Man Yang, Gannie Tzoneva, Hector Martinez, Carlo Sidore, Michael D Kessler and 49 more

Abstract read
In one paragraph

Article in Nature genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Mucosal implications of oral Jak3-targeted drugs in COVID patients.Molecular medicine (Cambridge, Mass.) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

59 authors.

Jack A KosmickiRegeneron Genetics Center, Tarrytown, NY, USA.
Anthony MarckettaRegeneron Genetics Center, Tarrytown, NY, USA.
Deepika SharmaRegeneron Genetics Center, Tarrytown, NY, USA.
Silvio Alessandro Di GioiaRegeneron Genetics Center, Tarrytown, NY, USA.
Samantha BatistaRegeneron Genetics Center, Tarrytown, NY, USA.
Xiao-Man YangRegeneron Genetics Center, Tarrytown, NY, USA.
Gannie TzonevaRegeneron Genetics Center, Tarrytown, NY, USA.
Hector MartinezRegeneron Genetics Center, Tarrytown, NY, USA.
Carlo SidoreRegeneron Genetics Center, Tarrytown, NY, USA.
Michael D KesslerRegeneron Genetics Center, Tarrytown, NY, USA.
Julie E HorowitzRegeneron Genetics Center, Tarrytown, NY, USA.
Genevieve H L RobertsAncestryDNA, Lehi, UT, USA.
Anne E JusticeGeisinger, Danville, PA, USA.ORCID http://orcid.org/0000-0002-8903-8712
Nilanjana BanerjeeRegeneron Genetics Center, Tarrytown, NY, USA.
Marie V CoignetAncestryDNA, Lehi, UT, USA.
Joseph B LeaderGeisinger, Danville, PA, USA.
Danny S ParkAncestryDNA, Lehi, UT, USA.
Rouel LancheRegeneron Genetics Center, Tarrytown, NY, USA.
Evan MaxwellRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0002-7325-7531
Spencer C KnightAncestryDNA, Lehi, UT, USA.
Xiaodong BaiRegeneron Genetics Center, Tarrytown, NY, USA.
Harendra GuturuAncestryDNA, Lehi, UT, USA.
Asher BaltzellAncestryDNA, Lehi, UT, USA.
Ahna R GirshickAncestryDNA, Lehi, UT, USA.
Shannon R McCurdyAncestryDNA, Lehi, UT, USA.
Raghavendran ParthaAncestryDNA, Lehi, UT, USA.
Adam J MansfieldRegeneron Genetics Center, Tarrytown, NY, USA.
David A TurissiniAncestryDNA, Lehi, UT, USA.
Miao ZhangAncestryDNA, Lehi, UT, USA.
Joelle MbatchouRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0002-2245-3743
Kyoko WatanabeRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0002-3303-8860
Anurag VermaDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Giorgio SirugoDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Colorado Center for Precision Medicine
Mayo Clinic Project Generation
Regeneron Genetics Center
University of California Los Angeles ATLAS Collaboration
Marylyn D RitchieDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-1208-1720
William J SalernoRegeneron Genetics Center, Tarrytown, NY, USA.
Alan R ShuldinerRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0001-9921-4305
Daniel J RaderDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-9245-9876
Tooraj MirshahiGeisinger, Danville, PA, USA.
Jonathan MarchiniRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0003-0610-8322
John D OvertonRegeneron Genetics Center, Tarrytown, NY, USA.
David J CareyGeisinger, Danville, PA, USA.
Lukas HabeggerRegeneron Genetics Center, Tarrytown, NY, USA.
Jeffrey G ReidRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0001-8645-4713
Aris EconomidesRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0002-6508-8942
Christos KyratsousRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0002-2596-2906
Katia KaralisRegeneron Genetics Center, Tarrytown, NY, USA.
Alina BaumRegeneron Genetics Center, Tarrytown, NY, USA.
Michael N CantorRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0002-1074-1203
Kristin A RandAncestryDNA, Lehi, UT, USA.
Eurie L HongAncestryDNA, Lehi, UT, USA.
Catherine A BallAncestryDNA, Lehi, UT, USA.
Katherine SiminovitchRegeneron Genetics Center, Tarrytown, NY, USA.
Aris BarasRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0002-6830-3396
Goncalo R AbecasisRegeneron Genetics Center, Tarrytown, NY, USA. goncalo.abecasis@regeneron.com.ORCID http://orcid.org/0000-0003-1509-1825
Manuel A R FerreiraRegeneron Genetics Center, Tarrytown, NY, USA. manuel.ferreira@regeneron.com.ORCID http://orcid.org/0000-0001-9059-1825

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
NCATS NIH HHS UL1 TR001878NCATS NIH HHS UL1 TR001881
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) and influenza are respiratory illnesses caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses, respectively. Both diseases share symptoms and clinical risk factors

Indexed as

COVID-19Genetic Predisposition to DiseaseGenome-Wide Association StudyInfluenza, HumanSARS-CoV-2Case-Control StudiesFemaleHumansMaleMiddle AgedPolymorphism, Single NucleotideRisk Factors

Identifiers

PMID39103650
PMCPMC11319199

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.