Evidence map›Paper›PMID 39103646›Full record

ArticleIntensive care medicine experimental2024

Standard versus individualised positive end-expiratory pressure (PEEP) compared by electrical impedance tomography in neurocritical care: a pilot prospective single centre study.

Vera Spatenkova, Mikulas Mlcek, Alan Mejstrik, Lukas Cisar, Eduard Kuriscak

Abstract read
In one paragraph

Article in Intensive care medicine experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vera SpatenkovaNeurocenter, Neurointensive Care Unit, Regional Hospital Liberec, Husova 357/10, 460 01, Liberec, Czech Republic. vera.spatenkova@nemlib.cz.ORCID http://orcid.org/0000-0003-4989-0967
Mikulas MlcekInstitute of Physiology, First Faculty of Medicine, Charles University in Prague, Albertov 5, 128 00, Prague, Czech Republic.
Alan MejstrikInstitute of Physiology, First Faculty of Medicine, Charles University in Prague, Albertov 5, 128 00, Prague, Czech Republic.
Lukas CisarTechnical Department, Regional Hospital Liberec, Husova 357/10, 460 01, Liberec, Czech Republic.
Eduard KuriscakInstitute of Physiology, First Faculty of Medicine, Charles University in Prague, Albertov 5, 128 00, Prague, Czech Republic.

Funding

TACR FW01010679
6 · The paper itself

Abstract

backgroundIndividualised bedside adjustment of mechanical ventilation is a standard strategy in acute coma neurocritical care patients. This involves customising positive end-expiratory pressure (PEEP), which could improve ventilation homogeneity and arterial oxygenation. This study aimed to determine whether PEEP titrated by electrical impedance tomography (EIT) results in different lung ventilation homogeneity when compared to standard PEEP of 5 cmH

methodsIn this prospective single-centre study, we evaluated 55 acute adult neurocritical care patients starting controlled ventilation with PEEPs close to 5 cmH

resultsThe mean PEEP value before titration was 4.75 ± 0.94 cmH

conclusionAdjusting PEEP to values derived from PEEP titration guided by EIT does not provide any significant changes in ventilation homogeneity as assessed by EIT to ventilated patients with healthy lungs, provided the change in PEEP does not exceed three cmH

Indexed as

Brain injuryElectrical impedance tomographyMechanical ventilationPEEP titrationPositive end-expiratory pressure (PEEP)Ventilation homogeneity

Identifiers

PMID39103646
PMCPMC11300775

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.