Evidence map›Paper›PMID 39103616›Full record

SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024

Incidence and prognostic factors of residual back pain in patients treated for osteoporotic vertebral compression fractures: a systematic review and meta-analysis.

Xiong-Gang Yang, Yue-Qiu Dong, Xiang Liu, Xiao-Liang Liu, Hao-Tian Luo, Yi Bao, Zhi Peng, Yu Zhao, Qiang Yang, Sheng Lu

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Developing and validating a combined model with CT-based paraspinal muscle radiomics and clinical features to predict residual low back pain after percutaneous kyphoplasty.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiong-Gang Yang *Department of Orthopedic Surgery, the Key Laboratory of Digital Orthopaedics of Yunnan Province, the First People's Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road, Xishan District, Kunming City, 650034, Yunnan Province, China.
Yue-Qiu Dong *Department of Rehabilitation, Affiliated Hospital of Hebei University of Technology, Handan City, 056000, Hebei Province, China.
Xiang LiuDepartment of Orthopedic Surgery, the Key Laboratory of Digital Orthopaedics of Yunnan Province, the First People's Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road, Xishan District, Kunming City, 650034, Yunnan Province, China.
Xiao-Liang LiuDepartment of Orthopedic Surgery, the Key Laboratory of Digital Orthopaedics of Yunnan Province, the First People's Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road, Xishan District, Kunming City, 650034, Yunnan Province, China.
Hao-Tian LuoDepartment of Orthopedic Surgery, the Key Laboratory of Digital Orthopaedics of Yunnan Province, the First People's Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road, Xishan District, Kunming City, 650034, Yunnan Province, China.
Yi BaoDepartment of Orthopedic Surgery, the Key Laboratory of Digital Orthopaedics of Yunnan Province, the First People's Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road, Xishan District, Kunming City, 650034, Yunnan Province, China.
Zhi PengDepartment of Orthopedic Surgery, the Key Laboratory of Digital Orthopaedics of Yunnan Province, the First People's Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road, Xishan District, Kunming City, 650034, Yunnan Province, China.
Yu ZhaoDepartment of Orthopaedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.
Qiang YangDepartment of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, 30021, China.
Sheng LuDepartment of Orthopedic Surgery, the Key Laboratory of Digital Orthopaedics of Yunnan Province, the First People's Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road, Xishan District, Kunming City, 650034, Yunnan Province, China. drlusheng@163.com.

Funding

Major Science and Technology Project of Yunnan Province Science and Technology Plan 202102AA310042Project of Yunnan Key Laboratory of Digital Orthopedics 202005AG070004Yunnan Medical Leading Talents Project L-2019006Yunnan Orthopedics and Sports Rehabilitation Clinical Medical Research Center 202102AA310068Yunnan Province "Ten Thousand People Plan" Famous Medical Project YNWR-MY-2019-058Yunnan Spinal Cord Disease Clinical Medical Center ZX2022000101
6 · The paper itself

Abstract

backgroundOsteoporotic vertebral compression fracture (OVCF) is a common consequence of osteoporosis and can significantly impact the quality of life for affected individuals. Despite treatment options such as vertebroplasty and kyphoplasty, many patients continue to experience residual back pain (RBP) even after the fracture has healed. The incidence of RBP after OVCF treatment varies among studies, and there is a need for further research to understand the risk factors associated with RBP.

methodsA systematic review and meta-analysis were conducted following the PRISMA guidelines. Electronic databases were searched, and relevant studies were selected based on inclusion and exclusion criteria. Data extraction and quality assessment were performed independently by two authors. Statistical analysis included single-proportion meta-analyses and pooling of odds ratios (OR) using the inverse-variance method, to calculate the overall incidences of RBP and cement leakage and identify risk factors associated with RBP.

resultsA total of 19 studies were included in the analysis. The overall incidences of RBP and cement leakage were found to be 16% and 18%, respectively. Several risk factors were identified, including gender, bone mineral density, depression, baseline visual analog scale (VAS) score, intravertebral vacuum cleft, number of fractured segments, cement distribution, history of vertebral fracture, thoracolumbar fascial injury, and fracture non-union.

conclusionsThis study provides potential value within the scope of the incidence and risk factors of RBP following treatment of OVCFs. The identified risk factors can help clinicians identify high-risk patients and tailor appropriate interventions. Future research should focus on standardizing the definition of RBP and patient selection criteria to improve the accuracy of estimates and facilitate better management strategies for OVCF patients.

Indexed as

Back PainFractures, CompressionOsteoporotic FracturesSpinal FracturesHumansIncidencePrognosisRisk FactorsVertebroplastyIncidenceMeta analysisOsteoporotic vertebral compression fractureResidual back painRisk factors

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.