Evidence map›Paper›PMID 39103540›Full record

ArticleEuropean journal of pediatrics2024

Cord blood vitamin E and lipids in infants born small for gestational age.

Guicun Yang, Nianrong Wang, Hao Liu, Lina Si, Yan Zhao

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Article in European journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Guicun YangDepartment of Pediatrics, Chongqing Health Center for Women and Children, Chongqing, China.
Nianrong WangDepartment of Pediatrics, Chongqing Health Center for Women and Children, Chongqing, China.
Hao LiuDepartment of Pediatrics, Chongqing Health Center for Women and Children, Chongqing, China.
Lina SiDepartment of Pediatrics, Chongqing Health Center for Women and Children, Chongqing, China.
Yan ZhaoDepartment of Pediatrics, Chongqing Health Center for Women and Children, Chongqing, China. 112008@hospital.cqmu.edu.cn.

Funding

Joint project of Chongqing Health Commission and Science and Technology Bureau 2021MSXM211Natural Science Foundation of Chongqing cstc2020jcyj-msxmX0527
6 · The paper itself

Abstract

Vitamin E is associated with the regulation of lipid metabolism. Our previous study revealed an inverse relationship between birth weight and cord blood vitamin E levels, suggesting a potential link between vitamin E and fetal growth. The aim of this study was to determine the association between vitamin E with fetal growth and lipids. In this investigation, a study involving 146 mother-infant pairs was performed. Cord plasma concentrations of vitamin E and lipids were measured. Our findings showed that cord plasma vitamin E levels were elevated in small for gestational age (SGA) infants, and higher vitamin E levels were associated with an increased risk of SGA (OR = 2.239, 95% CI 1.208, 4.742). Additionally, among lipid levels, higher cord plasma triglyceride (TG) levels were associated with increased risks of SGA (OR = 97.020, 95% CI 5.137, 1832.305), whereas after adjusting for confounding factors, the risk became no longer statistically significant. We also found a positive correlation between cord blood vitamin E concentrations and lipid levels.

conclusionelevated cord blood vitamin E concentrations may be associated with a higher risk of SGA and are positively correlated with lipid levels, suggesting a potential role for vitamin E in fetal lipid metabolism. WHAT IS KNOWN: • Vitamin E is associated with the regulation of lipid metabolism. • Vitamin E is inversely related to birth weight. WHAT IS NEW: • Elevated cord blood vitamin E concentrations may be associated with a higher risk of SGA and positively correlated with lipid levels.

Indexed as

Fetal BloodInfant, Small for Gestational AgeVitamin EAdultBirth WeightFemaleFetal DevelopmentHumansInfant, NewbornLipid MetabolismLipidsMalePregnancyLipidsVitamin ELipidSmall for gestational ageUmbilical cord bloodVitamin E

Identifiers

PMID39103540

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.