Observational studyJournal of perinatology : official journal of the California Perinatal Association2024
Oral sodium supplementation on growth and hypertension in preterm infants: an observational cohort study.
Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sodium supplementation strategies in preterm infants: effects on growth, electrolyte balance, and exploratory evidence on neurodevelopment - a systematic review and meta-analysis.BMC nutrition · 2026Pooled it
- Maternal low sodium intake and early postnatal diuretics program metabolic and ventilatory dysfunction in mice.Pediatric research · 2026Article
- The Changing Landscape of Sodium Needs in the Preterm Neonate for Optimizing Growth and Development.Nutrients · 2026Review
- Sodium Supplementation Algorithm to Promote Growth in Infants Who Are Preterm: Randomized Clinical Trial.Pediatrics open science · 2026Article
- Somatic growth outcomes in response to an individualized neonatal sodium supplementation protocol.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the association between enteral sodium supplementation on growth and hypertension (HTN) in preterm infants. STUDY
designA retrospective cohort study of infants born between 22-32 weeks and weighing 450-1500 grams (N = 821). Enteral sodium supplementation amounts, systolic blood pressures (SBP), weight gain, and other infant and maternal risk factors for HTN were electronically extracted.
resultsInfants receiving sodium supplementation were smaller and less mature. Sodium supplementation improved serum sodium levels, weight gain, and head circumference growth without causing hypernatremia. There was no correlation between urine and serum sodium or urine sodium and weight gain. Although infants receiving sodium had higher average SBP and rates of HTN, analysis demonstrated sodium supplementation did not increase odds of hypertension (OR
conclusionsIn preterm infants with poor weight gain, enteral sodium supplementation improved growth without increasing hypertension or hypernatremia.
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Identifiers
39103473What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.