Evidence map›Paper›PMID 39102701›Full record

ArticleHealth expectations : an international journal of public participation in health care and health policy2024

'It's a job to be done'. Managing polypharmacy at home: A qualitative interview study exploring the experiences of older people living with frailty.

Giorgia Previdoli, David P Alldred, Jonathan Silcock, Savi Tyndale-Biscoe, Daniel Okeowo, V-Lin Cheong, Beth Fylan

Abstract read
In one paragraph

Article in Health expectations : an international journal of public participation in health care and health policy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Supporting Older People Living With Frailty to Self-Manage Multiple Medicines: An Experience-Based Co-Design of a Complex Intervention Developed in UK Primary Care.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  5. 'It's a job to be done'. Managing polypharmacy at home: A qualitative interview study exploring the experiences of older people living with frailty.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giorgia PrevidoliSchool of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, UK.ORCID 0000-0002-9932-0586
David P AlldredNIHR Yorkshire and Humber Patient Safety Research Collaboration, Bradford, UK.ORCID 0000-0002-2525-4854
Jonathan SilcockSchool of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, UK.ORCID 0000-0002-4920-9249
Savi Tyndale-BiscoeBradford Teaching Hospitals NHS Foundation Trust, Bradford, UK.
Daniel OkeowoNIHR Yorkshire and Humber Patient Safety Research Collaboration, Bradford, UK.ORCID 0000-0003-3219-4439
V-Lin CheongLeeds Teaching Hospitals NHS Trust, Leeds, UK.ORCID 0000-0001-9938-1592
Beth FylanSchool of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, UK.ORCID 0000-0003-0599-4537

Funding

National Institute for Health and Care Research (NIHR) NIHR201056National Institute for Health and Care Research (NIHR) Yorkshire and Humber Patient Safety Translational Research Centre
6 · The paper itself

Abstract

introductionMany older people live with both multiple long-term conditions and frailty; thus, they manage complex medicines regimens and are at heightened risk of the consequences of medicines errors. Research to enhance how people manage medicines has focused on adherence to regimens rather than on the wider skills necessary to safely manage medicines, and the older population living with frailty and managing multiple medicines at home has been under-explored. This study, therefore, examines in depth how older people with mild to moderate frailty manage their polypharmacy regimens at home.

methodsBetween June 2021 and February 2022, 32 patients aged 65 years or older with mild or moderate frailty and taking five or more medicines were recruited from 10 medical practices in the North of England, United Kingdom, and the CARE 75+ research cohort. Semi-structured interviews were conducted face to face, by telephone or online. The interviews were recorded, transcribed verbatim and analysed using reflexive thematic analysis.

findingsFive themes were developed: (1) Managing many medicines is a skilled job I didn't apply for; (2) Medicines keep me going, but what happened to my life?; (3) Managing medicines in an unclear system; (4) Support with medicines that makes my work easier; and (5) My medicines are familiar to me-there is nothing else I need (or want) to know. While navigating fragmented care, patients were expected to fit new medicines routines into their lives and keep on top of their medicines supply. Sometimes, they felt let down by a system that created new obstacles instead of supporting their complex daily work.

conclusionFrail older patients, who are at heightened risk of the impact of medicines errors, are expected to perform complex work to safely self-manage multiple medicines at home. Such a workload needs to be acknowledged, and more needs to be done to prepare people in order to avoid harm from medicines. PATIENT AND PUBLIC INVOLVEMENT: An older person managing multiple medicines at home was a core member of the research team. An advisory group of older patients and family members advised the study and was involved in the first stages of data analysis. This influenced how data were coded and themes shaped.

Indexed as

Interviews as TopicPolypharmacyQualitative ResearchAgedAged, 80 and overEnglandFemaleFrail ElderlyFrailtyHumansMaleMedication AdherenceUnited Kingdomfrailtymedications managementmedications self‐managementolder peoplepolypharmacyqualitative study

Identifiers

PMID39102701
PMCPMC10777610

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.