Evidence map›Paper›PMID 39102544›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

ZNF91 is an endogenous repressor of the molecular phenotype associated with X-linked dystonia-parkinsonism (XDP).

Jimi L Rosenkrantz, J Elias Brandorff, Sanaz Raghib, Ashni Kapadia, Christine A Vaine, D Cristopher Bragg, Grace Farmiloe, Frank M J Jacobs

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jimi L RosenkrantzFaculty of Science, Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1098 XH, The Netherlands.ORCID 0000-0003-4425-884X
J Elias BrandorffFaculty of Science, Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1098 XH, The Netherlands.
Sanaz RaghibFaculty of Science, Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1098 XH, The Netherlands.ORCID 0009-0005-7897-1805
Ashni KapadiaFaculty of Science, Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1098 XH, The Netherlands.
Christine A VaineThe Collaborative Center for X-linked Dystonia-Parkinsonism, Massachusetts General Hospital, Boston, MA 02129.
D Cristopher BraggThe Collaborative Center for X-linked Dystonia-Parkinsonism, Massachusetts General Hospital, Boston, MA 02129.
Grace FarmiloeFaculty of Science, Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1098 XH, The Netherlands.
Frank M J JacobsFaculty of Science, Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1098 XH, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

X-linked dystonia-parkinsonism (XDP) is a severe neurodegenerative disorder resulting from an inherited intronic SINE-Alu-VNTR (SVA) retrotransposon in the

Indexed as

Dystonic DisordersGenetic Diseases, X-LinkedPhenotypeG-QuadruplexesHistone AcetyltransferasesHumansMaleRepressor ProteinsRetroelementsTATA-Binding Protein Associated FactorsTranscription Factor TFIIDHistone AcetyltransferasesRepressor ProteinsRetroelementsTATA-binding protein associated factor 250 kDaTATA-Binding Protein Associated FactorsTranscription Factor TFIIDG-quadruplex (G4)Krüppel-associated zinc finger protein 91 (ZNF91)neurodegenerationSINE-Alu-VNTR (SVA)X-linked dystonia–parkinsonism (XDP)

Identifiers

PMID39102544
PMCPMC11331120

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.