Evidence map›Paper›PMID 39102518›Full record

ArticleGigaScience2024

CAT: a computational anatomy toolbox for the analysis of structural MRI data.

Christian Gaser, Robert Dahnke, Paul M Thompson, Florian Kurth, Eileen Luders, The Alzheimer's Disease Neuroimaging Initiative

Abstract read
In one paragraph

Article in GigaScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 798 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
798citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

798 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Imaging insights into temporal lobe epilepsy: an AES-SDM meta-analysis and retrospective cohort study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
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  14. [European journal of nuclear medicine and molecular imaging · 2026
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  16. Network-dependent remote effects and local tau burden jointly shape neuronal dysfunction in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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  18. A frontotemporal dementia-like phenotype in schizophrenia: links to striatal dopamine and iron accumulation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Observational
  19. Brain microstructure mediates the relationship between Alzheimer's proteinopathies and memory.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  20. Article

738 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christian GaserDepartment of Psychiatry and Psychotherapy, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0002-9940-099X
Robert DahnkeDepartment of Psychiatry and Psychotherapy, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0002-7478-7489
Paul M ThompsonImaging Genetics Center, Stevens Neuroimaging & Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0002-4720-8867
Florian KurthSchool of Psychology, University of Auckland, Auckland 1142, New Zealand.ORCID 0000-0002-3807-473X
Eileen LudersSchool of Psychology, University of Auckland, Auckland 1142, New Zealand.ORCID 0000-0001-8273-7177
The Alzheimer's Disease Neuroimaging Initiative

Funding

Brain and behavior in individuals with intersex conditionsR01HD081720 · NICHD · UNIVERSITY OF CAMBRIDGE · PI HINES, MELISSA, LUEDERS, EILEEN · 2015 to 2020
$1.8M
NICHD NIH HHS R01 HD081720NIH HHS R01HD081720University of Auckland
6 · The paper itself

Abstract

A large range of sophisticated brain image analysis tools have been developed by the neuroscience community, greatly advancing the field of human brain mapping. Here we introduce the Computational Anatomy Toolbox (CAT)-a powerful suite of tools for brain morphometric analyses with an intuitive graphical user interface but also usable as a shell script. CAT is suitable for beginners, casual users, experts, and developers alike, providing a comprehensive set of analysis options, workflows, and integrated pipelines. The available analysis streams-illustrated on an example dataset-allow for voxel-based, surface-based, and region-based morphometric analyses. Notably, CAT incorporates multiple quality control options and covers the entire analysis workflow, including the preprocessing of cross-sectional and longitudinal data, statistical analysis, and the visualization of results. The overarching aim of this article is to provide a complete description and evaluation of CAT while offering a citable standard for the neuroscience community.

Indexed as

BrainImage Processing, Computer-AssistedMagnetic Resonance ImagingSoftwareBrain MappingComputational BiologyHumansNeuroimagingAlzheimer’s diseasebrainCAT12computational anatomycortical foldingcortical surfacecortical thicknesslongitudinalmorphometryMRIROISPM12VBM

Identifiers

PMID39102518
PMCPMC11299546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.