Evidence map›Paper›PMID 39102463›Full record

Trial reportAmerican journal of physiology. Regulatory, integrative and comparative physiology2024

Activation of skeletal muscle mechanoreceptors and nociceptors reduces the exercise performance of the contralateral homologous muscles.

Fabio Zambolin, Fabio Giuseppe Laginestra, Thomas Favaretto, Gaia Giuriato, Matteo Maria Ottaviani, Federico Schena, Pablo Duro-Ocana, Jamie Stewart McPhee, Massimo Venturelli

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of physiology. Regulatory, integrative and comparative physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fabio ZambolinDepartment of Sport and Exercise Sciences, Manchester Metropolitan University, Manchester, United Kingdom.ORCID 0000-0002-4178-6965
Fabio Giuseppe LaginestraDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.ORCID 0000-0003-4767-7249
Thomas FavarettoDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Gaia GiuriatoDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.ORCID 0000-0002-8149-9450
Matteo Maria OttavianiDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.ORCID 0000-0002-6354-3278
Federico SchenaDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.ORCID 0000-0002-2052-5117
Pablo Duro-OcanaDepartment of Life Sciences, Manchester Metropolitan University, Manchester, United Kingdom.
Jamie Stewart McPheeDepartment of Sport and Exercise Sciences, Manchester Metropolitan University, Manchester, United Kingdom.ORCID 0000-0002-3659-0773
Massimo VenturelliDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.ORCID 0000-0002-2469-8787

Funding

Brain Research Foundation Verona Onlus (MIUR) N/AEC | Horizon 2020 Framework Programme (H2020) 801604
6 · The paper itself

Abstract

Increasing evidence suggests that activation of muscle nerve afferents may inhibit central motor drive, affecting contractile performance of remote exercising muscles. Although these effects are well documented for metaboreceptors, very little is known about the activation of mechano- and mechanonociceptive afferents on performance fatigability. Therefore, the purpose of the present study was to examine the influence of mechanoreceptors and nociceptors on performance fatigability. Eight healthy young males undertook four randomized experimental sessions on separate occasions in which the experimental knee extensors were the following:

Indexed as

MechanoreceptorsMuscle FatigueMuscle, SkeletalMyalgiaNociceptorsAdultExerciseHumansIsometric ContractionMaleMuscle ContractionYoung Adultexercise-induced muscle damageexercise performancemuscle nerve afferentsneuromuscular fatiguestretching

Identifiers

PMID39102463
PMCPMC11483073

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.