Evidence map›Paper›PMID 39102391›Full record

ArticlePLOS global public health2024

Mild and moderate COVID-19 during Alpha, Delta and Omicron pandemic waves in urban Maputo, Mozambique, December 2020-March 2022: A population-based surveillance study.

Brecht Ingelbeen, Victória Cumbane, Ferão Mandlate, Barbara Barbé, Sheila Mercedes Nhachungue, Nilzio Cavele, Cremildo Manhica, Catildo Cubai, Neusa Maimuna Carlos Nguenha, Audrey Lacroix and 9 more

Abstract read
In one paragraph

Article in PLOS global public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Brecht IngelbeenInstituut voor Tropische Geneeskunde, Antwerp, Belgium.ORCID https://orcid.org/0000-0002-2214-6858
Victória CumbaneInstituto Nacional de Saúde, Ministry of Health, Marracuene, Mozambique.
Ferão MandlateInstituto Nacional de Saúde, Ministry of Health, Marracuene, Mozambique.ORCID https://orcid.org/0009-0008-4893-6576
Barbara BarbéInstituut voor Tropische Geneeskunde, Antwerp, Belgium.
Sheila Mercedes NhachungueInstituto Nacional de Saúde, Ministry of Health, Marracuene, Mozambique.
Nilzio CaveleInstituto Nacional de Saúde, Ministry of Health, Marracuene, Mozambique.
Cremildo ManhicaInstituto Nacional de Saúde, Ministry of Health, Marracuene, Mozambique.
Catildo CubaiInstituto Nacional de Saúde, Ministry of Health, Marracuene, Mozambique.ORCID https://orcid.org/0000-0002-6607-9554
Neusa Maimuna Carlos NguenhaInstituto Nacional de Saúde, Ministry of Health, Marracuene, Mozambique.
Audrey LacroixTransVIHMI (Recherches Translationnelles sur VIH et Maladies Infectieuses), Université de Montpellier, Institut de Recherche pour le Développement, INSERM, Montpellier, France.
Joachim MariënInstituut voor Tropische Geneeskunde, Antwerp, Belgium.ORCID https://orcid.org/0000-0001-7023-445X
Anja de WeggheleireMédecins sans Frontières, Brussels, Belgium.
Esther van KleefInstituut voor Tropische Geneeskunde, Antwerp, Belgium.
Philippe SelhorstInstituut voor Tropische Geneeskunde, Antwerp, Belgium.
Marianne A B van der SandeInstituut voor Tropische Geneeskunde, Antwerp, Belgium.
Martine PeetersTransVIHMI (Recherches Translationnelles sur VIH et Maladies Infectieuses), Université de Montpellier, Institut de Recherche pour le Développement, INSERM, Montpellier, France.
Marc-Alain WiddowsonInstituut voor Tropische Geneeskunde, Antwerp, Belgium.
Nalia IsmaelInstituto Nacional de Saúde, Ministry of Health, Marracuene, Mozambique.ORCID https://orcid.org/0000-0003-1793-9471
Ivalda MacicameInstituto Nacional de Saúde, Ministry of Health, Marracuene, Mozambique.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In sub-Saharan Africa, reported COVID-19 numbers have been lower than anticipated, even when considering populations' younger age. The extent to which risk factors, established in industrialised countries, impact the risk of infection and of disease in populations in sub-Saharan Africa, remains unclear. We estimated the incidence of mild and moderate COVID-19 in urban Mozambique and analysed factors associated with infection and disease in a population-based surveillance study. During December 2020-March 2022, 1,561 households (6,049 participants, median 21 years, 54.8% female, 7.3% disclosed HIV positive) of Polana Caniço, Maputo, Mozambique, were visited biweekly to report respiratory symptoms, anosmia, or ageusia, and self-administer a nasal swab for SARS-CoV-2 testing. Every three months, dried blood spots of a subset of participants (1,412) were collected for detection of antibodies against SARS-CoV-2 spike glycoprotein and nucleocapsid protein. Per 1000 person-years, 364.5 (95%CI 352.8-376.1) respiratory illness episodes were reported, of which 72.2 (95%CI 60.6-83.9) were COVID-19. SARS-CoV-2 seroprevalence rose from 4.8% (95%CI 1.1-8.6%) in December 2020 to 34.7% (95%CI 20.2-49.3%) in June 2021, when 3.0% were vaccinated. Increasing age, chronic lung disease, hypertension, and overweight increased risk of COVID-19. Older age increased the risk of SARS-CoV-2 seroconversion. We observed no association between socio-economic status, behaviour and COVID-19 or SARS-CoV-2 seroconversion. Active surveillance in an urban population confirmed frequent COVID-19 underreporting, yet indicated that the large majority of cases were mild and non-febrile. In contrast to reports from industrialised countries, social deprivation did not increase the risk of infection nor disease.

Identifiers

PMID39102391
PMCPMC11299809

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.