Evidence map›Paper›PMID 39102115›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2024

Flash Glucose Monitoring is Associated with HbA1c Improvement in Type 2 Diabetes Managed with Multiple Daily Injections of Insulin in the UK: A Retrospective Observational Study.

Karen A Adamson, Fraser W Gibb, James McLaren, Thinzar Min, Hermione Price, Sailesh Sankaranarayanan, Anna Strzelecka

Abstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karen A AdamsonDepartment of Diabetes and Endocrinology, Forth Valley Royal Hospital, NHS Forth Valley, Stirling Road, Larbert, FK5 4WR, Scotland. karen.adamson@nhs.scot.
Fraser W GibbEdinburgh Centre for Endocrinology and Diabetes, NHS Lothian, Edinburgh, Scotland.
James McLarenDepartment of Endocrinology and Diabetes, NHS Lanarkshire, Wishaw, Scotland.
Thinzar MinDiabetes Unit, Neath Port Talbot Hospital, Swansea Bay University Health Board, Port Talbot, Wales.
Hermione PriceResearch and Innovation Department, Southern Health NHS Foundation Trust, Southampton, England.
Sailesh SankaranarayananDepartment of Endocrinology and Diabetes, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, England.
Anna StrzeleckaDiabetes and Endocrinology Department, Northern Health and Social Care Trust, Antrim, Northern Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is a growing body of evidence demonstrating the benefit of flash glucose monitoring in people living with type 2 diabetes mellitus (T2DM). This real-world study aimed to evaluate the effect of initiating flash glucose monitoring on change in HbA1c after 3-6 months in adults living with T2DM treated with multiple daily injections of insulin.

methodsA retrospective observational study using data from ten clinical centres in the UK for adults with T2DM treated with multiple daily injections of insulin for at least 1 year was conducted. Patients who had been using the FreeStyle Libre/Libre 2 Flash Glucose Monitoring System for at least 3 months with baseline HbA1c 64-108 mmol/mol (8.0-12.0%) recorded up to 3 months prior to system use were included. Pregnant patients and those on dialysis were excluded. Patients with an HbA1c value measured 3-6 months after commencing flash glucose monitoring were included in the final analysis for evaluation of change.

resultsIn total, 87 patients were included in the final analysis (mean age, 60.0 ± 11.8 years, 60.9% male, mean body mass index (BMI), 31.6 ± 5.4 [mean ± SD]). From a mean baseline HbA1c of 80 ± 11 mmol/mol (9.5% ± 1.0%), HbA1c lowered by 11 ± 14 mmol/mol (1.0% ± 1.3%) at 3-6 months (p < 0.0001). A decrease was observed independent of age, baseline HbA1c, sex, duration of insulin use and BMI subgroups.

conclusionsInitiation of flash glucose monitoring was associated with a clinically and statistically significant improvement in HbA1c in a real-world setting at 3-6 months.

Indexed as

Basal-bolusContinuous glucose monitoringFlash glucose monitoringInsulinReal-worldType 2 diabetes

Identifiers

PMID39102115
PMCPMC11330429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.