Evidence map›Paper›PMID 39102069›Full record

ArticleJournal of autism and developmental disorders2026

Contextual Variables Associated with Challenging Behaviors in Adolescents with Fragile X Syndrome.

Nancy Brady, Kandace Fleming, Tyler Hicks, Heather Fielding-Gebhardt, Olivia Boorom

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nancy BradyDepartment of Speech Language Hearing Sciences and Disorders, University of Kansas, Lawrence, KS, 66049, USA. nbrady@ku.edu.ORCID http://orcid.org/0000-0001-7573-9000
Kandace FlemingLife Span Institute, University of Kansas, Lawrence, KS, USA.
Tyler HicksLife Span Institute, University of Kansas, Lawrence, KS, USA.
Heather Fielding-GebhardtLife Span Institute, University of Kansas, Lawrence, KS, USA.
Olivia BooromDepartment of Speech Language Hearing Sciences and Disorders, University of Kansas, Lawrence, KS, 66049, USA.

Funding

The Effects of Parenting on the Development and Behavior of Adolescents with FXSR01HD084563 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI NANCY CAROLINE BRADY · 2016 to 2026
$4.7M
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD084563NICHD NIH HHS R01 HD084563
6 · The paper itself

Abstract

purposeOur purpose was to report on a novel method of identifying variables associated with challenging behaviors in natural interactions between mothers and their adolescents with Fragile X syndrome (FXS).

methodsVideotaped interactions of 47 dyads interacting with an iPad game, completing a puzzle, and making a snack and were coded for challenging behaviors by adolescents with FXS, and maternal behaviors that preceded these behaviors. We described the frequencies of adolescent challenging behaviors, then used sequential and survival analyses to identify maternal and adolescent behaviors that preceded self-injurious behavior (SIB) and aggression.

resultsAcross all the dyads, 109 instances of SIB and 79 instances of aggression were identified during the 30 min of recorded interaction. Most of these challenging behaviors occurred during the iPad activity. The sequential analysis indicated that maternal requests for behavioral compliance frequently preceded both SIB and aggression. Survival analyses revealed that the likelihood of SIB or aggression was increased if the mothers requested behavioral compliance after the child engaged in another challenging behavior.

conclusionChallenging behaviors including SIB and aggression were frequently observed in many participants. The sequential and survival analyses were useful for identifying precursors to these behaviors. Further research is needed to investigate preventative strategies based on the results of sequential and survival analyses.

Indexed as

Adolescent BehaviorAggressionFragile X SyndromeMaternal BehaviorMother-Child RelationsProblem BehaviorSelf-Injurious BehaviorAdolescentChildFemaleHumansMaleAggressionDevelopmental disordersFragile X syndromeSelf-injurious behaviorSequential analysisSurvival analysisYoung people

Identifiers

PMID39102069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.