Evidence map›Paper›PMID 39102031›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2025

Contractile effects of stimulation of D

U Gergs, T H Pham, L M Rayo Abella, C Hesse, P Grundig, S Dhein, B Hofmann, J Neumann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Contractile effects of Aficamten in the human atrium.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  2. Clozapine acts as an antagonist of human dopamine DNaunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  3. Temperature alters the inotropic and chronotropic effect of DNaunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
  4. Contractile effects of stimulation of DNaunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

U GergsInstitute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, Magdeburger Straße 4, 06112, Halle (Saale), Germany.
T H PhamInstitute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, Magdeburger Straße 4, 06112, Halle (Saale), Germany.
L M Rayo AbellaInstitute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, Magdeburger Straße 4, 06112, Halle (Saale), Germany.
C HesseInstitute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, Magdeburger Straße 4, 06112, Halle (Saale), Germany.
P GrundigInstitute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, Magdeburger Straße 4, 06112, Halle (Saale), Germany.
S DheinRudolf Boehm Institute of Pharmacology and Toxicology, Medical Faculty, University Leipzig, Leipzig, Germany.
B HofmannDepartment of Cardiac Surgery, Mid-German Heart Center, University Hospital Halle, Halle (Saale), Germany.
J NeumannInstitute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, Magdeburger Straße 4, 06112, Halle (Saale), Germany. joachim.neumann@medizin.uni-halle.de.

Funding

DFG 519414516.
6 · The paper itself

Abstract

Dopamine receptors have been claimed not to directly increase contractility in the human heart. Therefore, we performed contraction experiments in isolated electrically driven human atrial preparations (HAP). For comparison, we performed contraction experiments with left atrial preparations of transgenic mice which harbor a cardiac overexpression of human D

Indexed as

Heart AtriaMyocardial ContractionReceptors, Dopamine D1AgedAnimalsDopamineDopamine AntagonistsDose-Response Relationship, DrugFemaleHumansMaleMiceMice, TransgenicMiddle AgedDopamineDopamine AntagonistsDRD1 protein, humanReceptors, Dopamine D1Force of contractionHuman atriumHuman dopamine 1 receptors

Identifiers

PMID39102031
PMCPMC11825631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.