Evidence map›Paper›PMID 39101990›Full record

ArticleHead and neck pathology2024

Oral Leishmaniasis in HIV-Positive and HIV-Negative Patients: A Comparative Analysis with Two New Case Reports.

Ana Cláudia Garcia Rosa, André Machado de Senna, Fabrício Passador Santos, Andresa Borges Soares, Vera Cavalcanti de Araújo

Abstract readCase ReportsComparative Study
In one paragraph

Article in Head and neck pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana Cláudia Garcia RosaFederal University of Tocantins, Medicine Course, Palmas, Tocantins, Brazil. anaclaudiagarcia@uft.edu.br.ORCID http://orcid.org/0000-0002-8566-3174
André Machado de SennaAfya Faculty of Medical Sciences, Dentistry Course, Palmas, Tocantins, Brazil.ORCID http://orcid.org/0000-0001-7800-8502
Fabrício Passador SantosDepartment of Oral Pathology, São Leopoldo Mandic School of Dentistry, Campinas, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-2777-8640
Andresa Borges SoaresDepartment of Oral Pathology, São Leopoldo Mandic School of Dentistry, Campinas, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-6112-3096
Vera Cavalcanti de AraújoDepartment of Oral Pathology, São Leopoldo Mandic School of Dentistry, Campinas, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-5860-3715

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis case report examines the clinical presentation, diagnosis, treatment, and outcomes of mucocutaneous leishmaniasis with primary oral involvement in HIV-positive and HIV-negative patients diagnosed in Brazil.

methodsWe discuss the clinical manifestations, diagnostic methods, and therapeutic strategies, highlighting the clinical and histopathologic diagnostic features and distinct progression patterns based on HIV status. Our findings are compared with patterns observed in other countries, emphasizing the differences between the Americas and Europe, Asia, and Africa.

resultsIn the Americas, particularly in Brazil, mucocutaneous leishmaniasis often presents with localized oral lesions, even in the presence of systemic immunosuppression, whereas in the Europe, Asia, and Africa, oral involvement is typically associated with visceral leishmaniasis in immunocompromised patients. These differences were due to variations in the parasite species involved.

conclusionThis comparison underscores the importance of regional and immunological factors in diagnosing and managing this neglected infectious disease.

Indexed as

Leishmaniasis, MucocutaneousHIV InfectionsHumansMouth DiseasesCutaneous LeishmaniasisHIV CoinfectionMucocutaneous LeishmaniasisMucous LeishmaniasisOral LeishmaniasisTegumentary LeishmaniasisVisceral Leishmaniasis

Identifiers

PMID39101990
PMCPMC11300730

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.