Evidence map›Paper›PMID 39101956›Full record

ReviewCurrent rheumatology reports2024

Calcium Pyrophosphate Crystal Deposition: Insights to Risks Factors and Associated Conditions.

Konstantinos Parperis, Argyris Constantinou

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Konstantinos ParperisDepartment of Medicine, Division of Rheumatology University of Arizona College of Medicine Phoenix, Phoenix, AZ, USA. parperis.konstantinos-marinos@ucy.ac.cy.ORCID http://orcid.org/0000-0001-6009-0130
Argyris ConstantinouUniversity of Cyprus Medical School, Nicosia, Cyprus.ORCID http://orcid.org/0009-0004-4609-7570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of the reviewThis review provides an overview of medical conditions and risk factors associated with CPPD. RECENT

findingsRecent studies have indicated that CPPD patients may have a higher risk for systemic conditions such as cardiovascular diseases. Calcium pyrophosphate deposition disease (CPPD) is a common crystal arthropathy that primarily affects older adults, and, in most cases, the aetiology is idiopathic. Age is the most remarkable risk factor and due to the aging population, the prevalence of this condition is expected to increase. Strong evidence supports an association between CPPD and several metabolic and endocrine conditions, including hemochromatosis, hyperparathyroidism, hypomagnesemia, and hypophosphatasia. Additionally, there is growing evidence of an increased risk for cardiovascular diseases among CPPD patients, alongside potential links to rheumatic disorders, gender, medications, and joint trauma. Further research is needed to explore the underlying mechanisms linking CPPD to associated conditions and to develop targeted therapies with the aim of improving patient outcomes.

Indexed as

ChondrocalcinosisCalcium PyrophosphateCardiovascular DiseasesHemochromatosisHumansHyperparathyroidismHypophosphatasiaRisk FactorsCalcium PyrophosphateCalcium Pyrophosphate Deposition DiseaseComorbiditiesCPPDPseudogoutRisk Factors

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.