Evidence map›Paper›PMID 39100918›Full record

ArticleFrontiers in chemistry2024

Liquid chromatography-mass spectrometry quantification of phytochemicals in

Luke C Marney, Jaewoo Choi, Armando Alcazar Magana, Liping Yang, Natascha Techen, Md Nure Alam, Mikah Brandes, Amala Soumyanath, Jan F Stevens, Claudia S Maier

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Nutraceutical Applications ofFoods (Basel, Switzerland) · 2026
    Review
  2. Withanolides Are Detected in Human Urine Following Oral Administration of aInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Evaluation of reversible cytochrome P450 inhibition by Withania somnifera leaf and root extracts.Drug metabolism and disposition: the biological fate of chemicals · 2025
    Article
  6. Ashwagandha (Journal of dietary supplements · 2025
    Article
  7. Review
  8. Antioxidants (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luke C MarneyDepartment of Chemistry, Oregon State University, Corvallis, OR, United States.
Jaewoo ChoiDepartment of Chemistry, Oregon State University, Corvallis, OR, United States.
Armando Alcazar MaganaDepartment of Chemistry, Oregon State University, Corvallis, OR, United States.
Liping YangDepartment of Chemistry, Oregon State University, Corvallis, OR, United States.
Natascha TechenBENFRA Botanical Dietary Supplements Research Center, Oregon Health and Science University, Portland, OR, United States.
Md Nure AlamDepartment of Chemistry, Oregon State University, Corvallis, OR, United States.
Mikah BrandesBENFRA Botanical Dietary Supplements Research Center, Oregon Health and Science University, Portland, OR, United States.
Amala SoumyanathBENFRA Botanical Dietary Supplements Research Center, Oregon Health and Science University, Portland, OR, United States.
Jan F StevensBENFRA Botanical Dietary Supplements Research Center, Oregon Health and Science University, Portland, OR, United States.
Claudia S MaierDepartment of Chemistry, Oregon State University, Corvallis, OR, United States.

Funding

Mechanisms underlying the cognitive effects of Centella asiatica water extract and constituent compounds in the 5xFAD mouse model of Alzheimer's DiseaseU19AT010829 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI SOUMYANATH, AMALA · 2020 to 2024
$6.1M
Ultra-Performance Liquid Chromatography Tandem Quadrupole Mass Spectrometry SystemS10OD026922 · OD · OREGON STATE UNIVERSITY · PI MAIER, CLAUDIA S · 2019 to 2019
$577k
Triple Quadrupole/Linear Ion Trap LC-MS/MS for LPIS10RR027878 · NCRR · OREGON STATE UNIVERSITY · PI STEVENS, JAN FREDERIK · 2010 to 2010
$484k
NCCIH NIH HHS U19 AT010829NCRR NIH HHS S10 RR027878NIH HHS S10 OD026922
6 · The paper itself

Abstract

Characterization of botanical extracts by mass spectrometry-based metabolomics analysis helps in determining the phytochemical composition that underlies their bioactivity and potential health benefits, while also supporting reproducibility of effects in clinical trials. The quantification of seven withanolides in

Indexed as

ashwagandhademing regressionmass spectrometrymetabolomicsmethod comparisonWithania somniferawithanolides

Identifiers

PMID39100918
PMCPMC11294917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.