Evidence map›Paper›PMID 39100862›Full record

ArticleGastro hep advances2024

Fatty Liver Education Promotes Physical Activity in Vulnerable Groups, Including Those With Unhealthy Alcohol Use.

Shyam Patel, Rebecca G Kim, Amy M Shui, Catherine Magee, Maggie Lu, Jennifer Chen, Michele Tana, Chiung-Yu Huang, Mandana Khalili

Abstract read
In one paragraph

Article in Gastro hep advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shyam PatelDivision of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, San Francisco, California.
Rebecca G KimDivision of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, San Francisco, California.
Amy M ShuiDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Catherine MageeDivision of Gastroenterology and Hepatology, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California.
Maggie LuDivision of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, San Francisco, California.
Jennifer ChenDivision of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, San Francisco, California.
Michele TanaDivision of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, San Francisco, California.
Chiung-Yu HuangDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Mandana KhaliliDivision of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, San Francisco, California.

Funding

UCSF Liver Core CenterP30DK026743 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Holger Willenbring · 1986 to 2026
$30.7M
Research Coordinating Center to Reduce Disparities in Multiple Chronic Diseases (RCC RD-MCD)U24MD017250 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHARLEBOIS, EDWIN DUNCAN, GANSKY, STUART A · 2021 to 2025
$22.9M
NRSA Hepatology Training GrantT32DK060414 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mandana Khalili, JACQUELYN J. MAHER · 2002 to 2026
$6.8M
Impact of the COVID-19 pandemic on patient outcomes, telehealth care delivery, and treatment for unhealthy alcohol use in vulnerable patients with advanced liver disease across two healthcare systemsR01AA029312 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KHALILI, MANDANA, SATRE, DEREK D · 2021 to 2025
$3.5M
Mentoring Multidisciplinary Patient-Oriented Research in Viral HepatitisK24AA022523 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KHALILI, MANDANA · 2013 to 2023
$1.9M
NIAAA NIH HHS K24 AA022523NIAAA NIH HHS R01 AA029312NIDDK NIH HHS P30 DK026743NIDDK NIH HHS T32 DK060414NIMHD NIH HHS U24 MD017250
6 · The paper itself

Abstract

BACKGROUND AND

aimsFatty liver disease (FLD), alcohol-associated and metabolically associated, often coexists. Increase in physical activity is associated with metabolic health and decreased FLD. We aimed to identify factors associated with physical activity and its improvement following FLD education in a racially diverse, vulnerable population.

methodsFrom February 19, 2020 to December 30, 2022, 314 adults with FLD at safety-net hepatology clinics in San Francisco were surveyed at baseline, immediately after FLD education, and at 6-month follow-up. After collecting clinical and sociodemographic data, logistic regression (adjusted for age, sex, and race/ethnicity) assessed factors associated with physical activity at baseline and its improvement following education.

resultsParticipant characteristics in those without vs with any physical activity were median age 49 vs 55 years, 64% vs 56% female, 66% vs 53% Hispanic race/ethnicity, 75% vs 55% obese, and 30% vs 22% consumed heavy alcohol, respectively. On multivariable analysis, older age was the only significant factor associated with physical activity at baseline (relative risk ratio 1.37 per decade increase, 95% confidence interval [CI] 1.07-1.75). Hispanic (vs non-Hispanic) participants had a significantly higher odds of improvement in physical activity (vs no change) 6 months after education (odds ratio 2.36, 95% CI 1.27-4.39). Among those with suboptimal or no physical activity at baseline, participants who consumed heavy alcohol (vs no drinking) had a significantly higher likelihood of achieving optimal physical activity following education (relative risk ratio 1.98, 95% CI 1.05-3.74).

conclusionDespite social and structural barriers, FLD education increased uptake of physical activity in vulnerable populations, especially among Hispanic individuals and those consuming heavy alcohol. Implementation of patient-centered education is important for FLD management.

Indexed as

Alcohol-Associated Liver DiseaseExerciseLifestyle ModificationNonalcoholic Fatty Liver DiseaseSteatotic liver diseaseUnderserved Populations

Identifiers

PMID39100862
PMCPMC11293529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.