Evidence map›Paper›PMID 39100859›Full record

ArticleToxicology research2024

Taurine exhibits antioxidant, anti-inflammatory, and antiapoptotic effects against pyraclostrobin exposure in rats.

Ibrahim Serim, Hasan Huseyin Demirel, Fahriye Zemheri-Navruz, Sinan Ince

Abstract read
In one paragraph

Article in Toxicology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ibrahim SerimFaculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Afyon Kocatepe University, 03200, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0002-7189-5804
Hasan Huseyin DemirelAfyon Kocatepe University, Bayat Vocational School, 03200, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0002-4795-2266
Fahriye Zemheri-NavruzFaculty of Science, Department of Molecular Biology and Genetics, Bartın University, 74100, Bartın, Turkey.ORCID https://orcid.org/0000-0003-1744-1091
Sinan InceFaculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Afyon Kocatepe University, 03200, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0002-1915-9797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyraclostrobin, a strobilurin-derived fungicide, causes oxidative stress and DNA damage in the organism. Taurine plays an important role in metabolic processes such as osmoregulatory, cytoprotective, and antioxidant effects. The study aimed to investigate the protective effect of taurine in Sprague Dawley male rats exposed to pyraclostrobin. The rats were separated into 6 groups and were found 8 animals in each group. Rats were given 30 mg/kg pyraclostrobin and pyraclostrobin together with three different taurine concentrations (50, 100, and 200 mg/kg) via oral gavage for 28 days. While pyraclostrobin increased biochemical parameters, lipid peroxidation, and DNA damage, it decreased glutathione levels and enzyme activities of catalase and superoxide dismutase. Pyraclostrobin increased apoptotic, proinflammatory, and

Indexed as

antiapoptoticanti-inflammatoryantioxidantpyraclostrobinrattaurine

Identifiers

PMID39100859
PMCPMC11295209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.