Evidence map›Paper›PMID 39100485›Full record

ArticleHeliyon2024

Socioeconomic differences in discrepancies between expected and experienced discomfort from colonoscopy and colon capsule endoscopy.

Ulrik Deding, Henrik Bøggild, Lasse Kaalby, Jacob Hjelmborg, Morten Kobaek-Larsen, Marianne Kirstine Thygesen, Benedicte Schelde-Olesen, Thomas Bjørsum-Meyer, Gunnar Baatrup, CareForColon2015 study group

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04049357 (Colon Capsule Endoscopy in Bowel Cancer Screening. A Randomized Controlled Trial), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04049357 nacompletednot on this map

Colon Capsule Endoscopy in Bowel Cancer Screening. A Randomized Controlled Trial

TypeinterventionalSponsorOdense University HospitalRan2020 to 2024Enrolled2,031ConditionsColorectal Cancer, AdenomaArmsCamera Capsule Endoscopy/ PillCam
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ulrik DedingDepartment of Clinical Research, University of Southern Denmark, Denmark.
Henrik BøggildPublic Health and Epidemiology, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
Lasse KaalbyDepartment of Clinical Research, University of Southern Denmark, Denmark.
Jacob HjelmborgDepartment of Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense, Denmark.
Morten Kobaek-LarsenDepartment of Clinical Research, University of Southern Denmark, Denmark.
Marianne Kirstine ThygesenDepartment of Clinical Research, University of Southern Denmark, Denmark.
Benedicte Schelde-OlesenDepartment of Clinical Research, University of Southern Denmark, Denmark.
Thomas Bjørsum-MeyerDepartment of Clinical Research, University of Southern Denmark, Denmark.
Gunnar BaatrupDepartment of Clinical Research, University of Southern Denmark, Denmark.
CareForColon2015 study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Social inequalities in colorectal cancer screening participation are evident. Barriers to screening participation include discomfort from diagnostic modalities. We aimed to describe the discomfort experienced from colonoscopy and colon capsule endoscopy (CCE) and investigate the discrepancy between expected and experienced discomfort stratified by socioeconomic status. Methods: A randomised controlled trial was conducted offering half of the colorectal cancer screening invitees the choice between CCE and colonoscopy after a positive faecal immunochemical test. This paper includes those who elected to undergo CCE. A positive CCE elicited referral for a therapeutic colonoscopy. Participants reported their discomfort from CCE and from any following colonoscopies in electronically distributed questionnaires. Discomfort was measured using visual analogue scales and compared between socioeconomic subgroups determined by educational level and income. Results: The experienced discomfort from CCE and colonoscopy differed significantly between educational levels but not income levels. The bowel preparation contributed the most to the experienced discomfort in both CCE and colonoscopy. The discrepancy between expected and experienced discomfort from colonoscopy increased with increasing educational and income levels. A similar trend was seen in CCE between educational levels but not income levels. Conclusions: None of the results indicated a higher discomfort in lower socioeconomic subgroups. Regardless of the investigation modality, the bowel preparation was the main contributor to experienced discomfort. The discrepancy between expected and experienced discomfort did not seem to be larger in lower socioeconomic subgroups, indicating that this is not a major barrier causing inequalities in screening uptake. This is the first study investigating individual discomfort discrepancy in both CCE and colonoscopy, while being able to stratify by socioeconomic status.

Indexed as

Colon capsule endoscopyColonoscopyColorectal cancer screeningInequalityPatient discomfortSocioeconomic status

Identifiers

PMID39100485
PMCPMC11295845

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.