Evidence map›Paper›PMID 39100473›Full record

ArticleHeliyon2024

Insights on the comparative affinity of ribonucleic acids with plant-based beta carboline alkaloid, harmine: Spectroscopic, calorimetric and computational evaluation.

Paromita Sarkar, Priyanka Gopi, Prateek Pandya, Samaresh Paria, Maidul Hossain, Manzer H Siddiqui, Saud Alamri, Kakali Bhadra

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paromita SarkarUniversity of Kalyani, Department of Zoology, Nadia, W. Bengal, 741235, India.
Priyanka GopiAmity Institute of Forensic Sciences, Amity University, Noida, Uttar Pradesh, India.
Prateek PandyaAmity Institute of Forensic Sciences, Amity University, Noida, Uttar Pradesh, India.
Samaresh PariaVidyasagar University, Department of Chemistry, Midnapore 721 102, West Bengal, India.
Maidul HossainVidyasagar University, Department of Chemistry, Midnapore 721 102, West Bengal, India.
Manzer H SiddiquiDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Saud AlamriDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Kakali BhadraUniversity of Kalyani, Department of Zoology, Nadia, W. Bengal, 741235, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small molecules as ligands target multifunctional ribonucleic acids (RNA) for therapeutic engagement. This study explores how the anticancer DNA intercalator harmine interacts various motifs of RNAs, including the single-stranded A-form poly (rA), the clover leaf tRNA

Indexed as

Beta-carboline alkaloidHarmineIsothermal calorimetryMolecular dockingMolecular dynamicsPrincipal component analysis (PCA)Ribonucleic acids RNAsSpectroscopy

Identifiers

PMID39100473
PMCPMC11295990

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.