Evidence map›Paper›PMID 39100039›Full record

ArticleCureus2024

Role of MicroRNA-21 in Regulating Intracellular Pathways Associated With Phagocytosis in Human Macrophages: An In Vitro Study.

Natsuki Anada, Yoshinobu Nakayama, Jun Takeshita, Kyoko Kageyama, Hiroatsu Sakamoto, Takahiko Kamibayashi, Yasufumi Nakajima

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natsuki AnadaAnesthesiology and Intensive Care Medicine, Kansai Medical University, Hirakata, JPN.
Yoshinobu NakayamaAnesthesiology and Critical Care, Faculty of Medicine, Kindai University, Osakasayama, JPN.
Jun TakeshitaAnesthesiology and Critical Care, Osaka Women's and Children's Hospital, Osaka, JPN.
Kyoko KageyamaAnesthesiology and Intensive Care Medicine, Kansai Medical University, Hirakata, JPN.
Hiroatsu SakamotoAnesthesiology and Critical Care, Faculty of Medicine, Kindai University, Osakasayama, JPN.
Takahiko KamibayashiAnesthesiology and Intensive Care Medicine, Kansai Medical University, Hirakata, JPN.
Yasufumi NakajimaAnesthesiology and Critical Care, Faculty of Medicine, Kindai University, Osakasayama, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction The efficient clearance of bacteria by macrophages is crucial for the timely resolution of inflammation. In this study, we investigated the role of microRNA-21 (miR-21)-induced phagocytosis and its intracellular signaling pathways in human macrophages

Indexed as

inflammationintracellular signaling peptides and proteinsmacrophagemicrornamir-21phagocytosis

Identifiers

PMID39100039
PMCPMC11295782

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.