ArticleWorld journal of diabetes2024
Does type 1 diabetes serve as a protective factor against inflammatory bowel disease: A Mendelian randomization study.
Article in World journal of diabetes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Structural characterization and effect on diabetes mellitus with ulcerative colitis of polysaccharide fromFrontiers in nutrition · 2026Article
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Authors and funding
6 authors.
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Abstract
backgroundThe impact of type 1 diabetes (T1D) on inflammatory bowel disease (IBD) remains unclear.
aimTo analyze the causal relationship between T1D and IBD using Mendelian ran-domization (MR).
methodsSingle nucleotide polymorphisms were sourced from FinnGen for T1D, IBD, ulcerative colitis (UC) and Crohn's disease (CD). Inverse variance-weighted, MR-Egger, and weighted median tests were used to assess exposure-outcome causality. The MR-Egger intercept was used to assess horizontal pleiotropy. Co-chran's
resultsOur MR analysis indicated that T1D was associated with a reduced risk of IBD [odds ratio (OR): 0.959; 95% confidence interval (CI): 0.938-0.980;
conclusionThis MR analysis suggests that T1D serves as a potential protective factor against IBD and UC but is independent of CD.
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