Evidence map›Paper›PMID 39099582›Full record

ArticleEpilepsy & behavior reports2024

Refractory inflammatory hydrocephalus: A case report of a rare and complicated delayed sequelae following cerebral hemispherectomy surgery for epilepsy.

Akshay Sharma, Efstathios Kondylis, Shaarada Srivatsa, Nehaw Sarmey, Deepak Lachhwani, Laura Nedorezov, William Bingaman

Abstract readCase Reports
In one paragraph

Article in Epilepsy & behavior reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Akshay SharmaDepartment of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
Efstathios KondylisDepartment of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
Shaarada SrivatsaDepartment of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
Nehaw SarmeyDepartment of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
Deepak LachhwaniEpilepsy Center, Cleveland Clinic Foundation, Cleveland, OH, USA.
Laura NedorezovCenter of Pediatric Rheumatology and Immunology, Cleveland Clinic Foundation, Cleveland, OH, USA.
William BingamanDepartment of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrocephalus is a known complication following surgical resection of a cerebral hemisphere for refractory epilepsy, yet the pathological mechanism remains poorly understood. We present a case of refractory aseptic inflammatory hydrocephalus following cerebral hemispherectomy surgery for refractory epilepsy treated with a combination of cerebral spinal fluid (CSF) diversion and immunosuppression via IL-1 receptor agonist, Anakinra. At 6 month follow up, the patient had returned to neurologic baseline, with improvement in school and physical therapy performance. Further investigation into the beneficial role of immunosuppressive therapy is needed to better understand the relationship between neuro-inflammation and improving outcomes following epilepsy surgery.

Indexed as

HemispherectomyHydrocephalusImmunomodulationPediatrics

Identifiers

PMID39099582
PMCPMC11296259

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.