Evidence map›Paper›PMID 39099545›Full record

ArticlePM & R : the journal of injury, function, and rehabilitation2025

Racial disparities in prosthesis abandonment and mobility outcomes after lower limb amputation from a dysvascular etiology in a veteran population.

Max Hurwitz, Joseph Czerniecki, David Morgenroth, Aaron Turner, Alison W Henderson, Beth Halsne, Daniel Norvell

Abstract read
In one paragraph

Article in PM & R : the journal of injury, function, and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Max HurwitzDepartment of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-9498-0999
Joseph CzernieckiVA Center for Limb Loss and Mobility (CLiMB), VA Puget Sound Health Care System, Seattle, Washington DC, USA.
David MorgenrothVA Center for Limb Loss and Mobility (CLiMB), VA Puget Sound Health Care System, Seattle, Washington DC, USA.ORCID https://orcid.org/0000-0002-0226-7775
Aaron TurnerVA Center for Limb Loss and Mobility (CLiMB), VA Puget Sound Health Care System, Seattle, Washington DC, USA.
Alison W HendersonVA Center for Limb Loss and Mobility (CLiMB), VA Puget Sound Health Care System, Seattle, Washington DC, USA.
Beth HalsneVA Center for Limb Loss and Mobility (CLiMB), VA Puget Sound Health Care System, Seattle, Washington DC, USA.ORCID https://orcid.org/0000-0003-0640-1051
Daniel NorvellVA Center for Limb Loss and Mobility (CLiMB), VA Puget Sound Health Care System, Seattle, Washington DC, USA.ORCID https://orcid.org/0000-0002-4386-2677

Funding

RRD VA I01 RX002919U.S. Department of Veterans Affairs 1 I01 RX002919R-01
6 · The paper itself

Abstract

backgroundNon-Hispanic Black (NHB) individuals have higher rates of amputation and increased risk of a transfemoral amputation due to dysvascular disease than non-Hispanic White (NHW) individuals. However, it is unclear if NHB individuals have differences in prosthesis use or functional outcomes following an amputation.

objectiveTo determine if there are racial disparities in prosthesis abandonment and mobility outcomes in veterans who have undergone their first major unilateral lower extremity amputation (LEA) due to diabetes and/or peripheral artery disease.

designNational cohort study that identified individuals retrospectively through the Veterans Affairs (VA) Corporate Data Warehouse (CDW) from March 1, 2018, to November 30, 2020, then prospectively collected their self-reported prosthesis abandonment and mobility. Multiple logistic regression was used to control for potential confounders and identify potential effect modifiers.

settingThe VA CDW, participant mailings and phone calls.

participantsThree hundred fifty-seven individuals who underwent an incident transtibial or transfemoral amputation due to diabetes and/or peripheral arterial disease.

interventionsNot applicable. MAIN OUTCOMES MEASURES: (1) Self-reported prosthesis abandonment. (2) Level of mobility assessed using the Locomotor Capabilities Index.

resultsRurally located NHB individuals without a major depressive disorder (MDD) had increased odds of abandoning their prosthesis (adjusted odds ratios [aOR] = 5.3; 95% confidence interval [CI]: [1.3-21.1]). This disparity was nearly three times as large for rurally located NHB individuals with MDD diagnosis, compared with other races from rural areas and with MDD (aOR = 15.8; 95% CI, 2.5-97.6). NHB individuals living in an urban area were significantly less likely to achieve advanced mobility, both with MDD (aOR=0.16; 95% CI: [0.04-7.0]) and without MDD (aOR = 0.26; 95% CI: [0.09-0.73]).

conclusionsThis study demonstrated that health care disparities persist for NHB veterans following a dysvascular LEA, with increased prosthesis abandonment and worse mobility outcomes.

Indexed as

Amputation, SurgicalArtificial LimbsBlack or African AmericanLower ExtremityPeripheral Arterial DiseaseVeteransAgedFemaleHumansMaleMiddle AgedMobility LimitationRetrospective StudiesUnited StatesWhiteWhite People

Identifiers

PMID39099545
PMCPMC11804270

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.