Evidence map›Paper›PMID 39099153›Full record

ArticlePediatric blood & cancer2024

Sexually transmitted infection testing and diagnosis in adolescents and young adults with sickle cell disease.

Joseph Walden, Joseph R Stanek, Ashley M Ebersole, Leena Nahata, Susan E Creary

Abstract read
In one paragraph

Article in Pediatric blood & cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph WaldenAbigail Wexner Research Institute, Center for Child Health Equity and Outcomes Research, Columbus, Ohio, USA.ORCID 0000-0002-4111-1845
Joseph R StanekDivision of Hematology/Oncology/BMT, Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio, USA.ORCID 0000-0003-1630-2102
Ashley M EbersoleDivision of Adolescent Medicine, Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio, USA.
Leena NahataAbigail Wexner Research Institute, Center for Biobehavioral Health, Columbus, Ohio, USA.ORCID 0000-0003-3899-2642
Susan E CrearyAbigail Wexner Research Institute, Center for Child Health Equity and Outcomes Research, Columbus, Ohio, USA.ORCID 0000-0002-4730-8139

Funding

Optimizing fertility preservation and decision quality in male AYA with cancer: A family-centered interventionK08CA237338 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI NAHATA, LEENA · 2019 to 2023
$1.0M
NCI NIH HHS K08 CA237338NCI NIH HHS K08CA237338NIH HHS
6 · The paper itself

Abstract

backgroundSexually transmitted infections (STIs) are common and disproportionately affect Black adolescents and young adults (AYAs). Less is known about STIs among Black AYAs with chronic conditions, such as sickle cell disease (AYAs-SCD). This study compared STI testing and diagnosis between AYAs-SCD and their peers, overall and among STI-related encounters. PROCEDURE: This retrospective, cross-sectional study used diagnosis and billing codes in the Pediatric Health Information System (PHIS) to identify inpatient and emergency department encounters from January 1, 2022 to May 31, 2023 among all AYAs 15-24 years and those with STI-related diagnoses (e.g., "cystitis"). STI testing and diagnosis rates were compared between AYAs-SCD, non-Black AYAs, and Black AYAs, controlling for age, sex, and encounter setting.

resultsWe identified 3602 AYAs-SCD, 177,783 Black AYAs, and 534,495 non-Black AYAs. AYAs-SCD were less likely to be tested for STIs than non-Black AYAs (odds ratio [OR] = 0.26; adj. p < .001) and Black AYAs (OR = 0.53; adj. p < .001). When tested, AYAs-SCD were more likely to be diagnosed with an STI than non-Black AYAs (OR = 2.39; adj. p = .006) and as likely as Black AYAs (OR = 0.67; adj. p = .15). Among STI-related encounters, AYAs-SCD were less likely to be tested than non-Black AYAs (OR = 0.18; adj. p < .001) and Black AYAs (OR = 0.44; adj. p < .001). No significant differences in STI diagnoses were found in this subset between AYAs-SCD and non-Black AYAs (OR = 0.32; adj. p = .28) or Black AYAs (OR = 1.07; adj. p = .99).

conclusionsSTI care gaps may disproportionately affect AYAs-SCD. STIs should be considered when evaluating symptomatic AYAs-SCD in acute settings. More research is needed to further contextualize STI care for AYAs-SCD.

Indexed as

Anemia, Sickle CellSexually Transmitted DiseasesAdolescentAdultBlack or African AmericanCross-Sectional StudiesFemaleFollow-Up StudiesHumansMaleRetrospective StudiesYoung Adultadolescenthealth disparityhealth equitysexually transmitted infectionsickle cell diseaseyoung adult

Identifiers

PMID39099153
PMCPMC11472860

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.