Evidence map›Paper›PMID 39099002›Full record

ArticleJournal of cosmetic dermatology2024

Transdermal characteristic study of bovine sialoglycoproteins with anti-skin aging and accelerating skin wound healing.

Hongwei Cheng, Xiangbo Li, Jiabao Du, Liuyi Dang, Shiyi Wang, Li Ding, Fan Zhang, Shisheng Sun, Zheng Li

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. α2-3-Sialylated Glycoproteins AttenuateInternational journal of molecular sciences · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongwei ChengLaboratory for Functional Glycomics, College of Life Sciences, Northwest University, Xi'an, China.
Xiangbo LiLaboratory for Functional Glycomics, College of Life Sciences, Northwest University, Xi'an, China.
Jiabao DuLaboratory for Functional Glycomics, College of Life Sciences, Northwest University, Xi'an, China.
Liuyi DangLaboratory for Functional Glycomics, College of Life Sciences, Northwest University, Xi'an, China.
Shiyi WangLaboratory for Functional Glycomics, College of Life Sciences, Northwest University, Xi'an, China.
Li DingLaboratory for Functional Glycomics, College of Life Sciences, Northwest University, Xi'an, China.
Fan ZhangLaboratory for Functional Glycomics, College of Life Sciences, Northwest University, Xi'an, China.
Shisheng SunLaboratory for Functional Glycomics, College of Life Sciences, Northwest University, Xi'an, China.ORCID https://orcid.org/0000-0002-7242-7164
Zheng LiLaboratory for Functional Glycomics, College of Life Sciences, Northwest University, Xi'an, China.ORCID https://orcid.org/0000-0002-1839-3450

Funding

the National Natural Science Foundation of China 82370592
6 · The paper itself

Abstract

backgroundSialoglycoproteins play important roles in various biological processes, including cell adhesion, immune response, and cell signaling. Our previous studies indicated that the bovine sialoglycoproteins could be developed as a reagent against skin aging and as a new candidate for accelerating skin wound healing as well as inhibiting scar formation. However, transdermal characteristic of the bovine sialoglycoproteins is still unknown.

aimsThis study investigated the transdermal permeation of the bovine sialoglycoproteins through porcine skin using the Franz diffusion cell method.

resultsOur study showed that the bovine sialoglycoproteins could penetrate through the porcine skin with a linear permeation pattern described by the regression equation N% = 11.49 t-3.858, with a high coefficient of determination (R

conclusionsParts of the bovine sialoglycoproteins with molecular weight less than 69.2 kDa had ability to traverse the epidermal barrier. Understanding the permeation characteristics of the bovine sialoglycoproteins for developing innovative formulations with therapeutic benefits, contributing to advancements in cosmetic and dermatological fields.

Indexed as

SialoglycoproteinsSkin AgingWound HealingAdministration, CutaneousAnimalsCattleEpidermisMolecular WeightSkinSkin AbsorptionSwineTandem Mass SpectrometrySialoglycoproteinsbovine sialoglycoproteinsFranz diffusion cell methodporcine skintransdermal characteristics

Identifiers

PMID39099002
PMCPMC11626321

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.