Evidence map›Paper›PMID 39098946›Full record

ArticleMalaria journal2024

Spatiotemporal patterns and association with climate for malaria elimination in Lao PDR: a hierarchical modelling analysis with two-step Bayesian model selection.

Chawarat Rotejanaprasert, Vilayvone Malaphone, Mayfong Mayxay, Keobouphaphone Chindavongsa, Virasack Banouvong, Boualam Khamlome, Phoutnalong Vilay, Viengxay Vanisavaeth, Richard J Maude

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Article in Malaria journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Chawarat RotejanaprasertDepartment of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. chawarat.rot@mahidol.ac.th.
Vilayvone MalaphoneMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Mayfong MayxayInstitute for Research and Education Development, University of Health Sciences, Vientiane, Lao PDR.
Keobouphaphone ChindavongsaCenter of Malariology, Parasitology, and Entomology, Vientiane, Lao PDR.
Virasack BanouvongCenter of Malariology, Parasitology, and Entomology, Vientiane, Lao PDR.
Boualam KhamlomeCenter of Malariology, Parasitology, and Entomology, Vientiane, Lao PDR.
Phoutnalong VilayCenter of Malariology, Parasitology, and Entomology, Vientiane, Lao PDR.
Viengxay VanisavaethCenter of Malariology, Parasitology, and Entomology, Vientiane, Lao PDR.
Richard J MaudeMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Funding

Bill and Melinda Gates Foundation OPP1193472_2018
6 · The paper itself

Abstract

backgroundThe government of Lao PDR has increased efforts to control malaria transmission in order to reach its national elimination goal by 2030. Weather can influence malaria transmission dynamics and should be considered when assessing the impact of elimination interventions but this relationship has not been well characterized in Lao PDR. This study examined the space-time association between climate variables and Plasmodium falciparum and Plasmodium vivax malaria incidence from 2010 to 2022.

methodsSpatiotemporal Bayesian modelling was used to investigate the monthly relationship, and model selection criteria were used to evaluate the performance of the models and weather variable specifications. As the malaria control and elimination situation was spatially and temporally dynamic during the study period, the association was examined annually at the provincial level.

resultsMalaria incidence decreased from 2010 to 2022 and was concentrated in the southern regions for both P. falciparum and P. vivax. Rainfall and maximum humidity were identified as most strongly associated with malaria during the study period. Rainfall was associated with P. falciparum incidence in the north and central regions during 2010-2011, and with P. vivax incidence in the north and central regions during 2012-2015. Maximum humidity was persistently associated with P. falciparum and P. vivax incidence in the south.

conclusionsMalaria remains prevalent in Lao PDR, particularly in the south, and the relationship with weather varies between regions but was strongest for rainfall and maximum humidity for both species. During peak periods with suitable weather conditions, vector control activities and raising public health awareness on the proper usage of intervention measures, such as indoor residual spraying and personal protection, should be prioritized.

Indexed as

Bayes TheoremClimateMalaria, FalciparumMalaria, VivaxSpatio-Temporal AnalysisDisease EradicationHumansIncidenceLaosPlasmodium vivaxWeatherClimateHierarchical modelingLao PDRMalariaSpatiotemporal

Identifiers

PMID39098946
PMCPMC11298089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.