Evidence map›Paper›PMID 39098921›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

Risk factors, incidence, and outcomes of neonatal respiratory extracorporeal membrane oxygenation including association with therapeutic hypothermia in California during 2013-2020.

Deepika Sankaran, Henry C Lee, Lidia Park, Peiyi Kan, Satyan Lakshminrusimha

Abstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Plasma brain-related biomarkers and potential therapeutic targets in pediatric ECMO.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Deepika SankaranDivision of Neonatology, Department of Pediatrics, University of California Davis, Sacramento, CA, USA. dsankaran@ucdavis.edu.ORCID 0000-0002-6704-6949
Henry C LeeDivision of Neonatology, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-8383-1720
Lidia ParkDivision of Neonatology, Department of Pediatrics, University of California Davis, Sacramento, CA, USA.
Peiyi KanDivision of Neonatology, Department of Pediatrics, Stanford University, Palo Alto, CA, USA.
Satyan LakshminrusimhaDivision of Neonatology, Department of Pediatrics, University of California Davis, Sacramento, CA, USA.ORCID 0000-0001-6098-2155

Funding

Institutional Career Development Core (KL2)KL2TR001859 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HOLMES, JAMES F. · 2016 to 2025
$10.1M
Optimal Oxygenation in Neonatal Lung InjuryR01HD072929 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Satyanarayana Lakshminrusimha · 2012 to 2026
$5.4M
Neonatal Hypovolemic Cardiac Arrest: Role of Early Rapid Volume ResuscitationR03HD109443 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SANKARAN, DEEPIKA · 2023 to 2023
$160k
NCATS NIH HHS KL2 TR001859NICHD NIH HHS R01 HD072929NICHD NIH HHS R03 HD109443U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) HD072929
6 · The paper itself

Abstract

objectiveTo evaluate the incidence, indications and outcomes with neonatal extracorporeal membrane oxygenation (ECMO) and its association with therapeutic hypothermia (TH) among infants undergoing invasive mechanical ventilation (IMV) in California during 2013-2020. STUDY

designWe analyzed data on neonates ≥34 weeks gestation with ≥4 h of IMV over an 8-year period (2013-2020) from the California Perinatal Quality Care Collaborative (CPQCC) database.

resultsBetween 2013 and 2020, the ranges for utilization of iNO (13.9 to 17.2%), ECMO (2.1 to 2.5%), TH (10.2 to 15.7%) and TH + ECMO (0.4 to 0.8%) were observed. The most common association with neonatal ECMO was TH (148 cases, OR 3.2, 95% CI 2.6-4.3, p < 0.01). The combination of meconium aspiration syndrome (MAS) and hypoxic ischemic encephalopathy (HIE) increased risk of iNO and ECMO use (OR 11.3, 1.5-86.9), p = 0.02).

conclusionVentilated infants ≥34 weeks gestational age undergoing TH are at risk for iNO/ECMO use and need close monitoring.

Indexed as

Extracorporeal Membrane OxygenationHypothermia, InducedHypoxia-Ischemia, BrainMeconium Aspiration SyndromeRespiration, ArtificialCaliforniaFemaleGestational AgeHumansIncidenceInfant, NewbornMaleRespiratory Distress Syndrome, NewbornRetrospective StudiesRisk Factors

Identifiers

PMID39098921
PMCPMC12702496

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.