ArticleCancer2024
Social isolation, depression, and anxiety among young adult cancer survivors: The mediating role of social connectedness.
Article in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- The lived experiences of social isolation among cancer patients: a systematic review and meta-synthesis.International journal of nursing studies advances · 2026Review
- Cognitive complaints and their associations with role functioning limitations among adolescent and young adult cancer survivors in Hong Kong.Asia-Pacific journal of oncology nursing · 2026Article
- Article
- Does Age Modify the Relationship Between Loneliness and Telehealth Use?Journal of general internal medicine · 2026Article
- The role of social engagement and support in the association between combined caregiver-cancer survivor status and depressive symptoms.The Gerontologist · 2026Article
- Psychological Impact of Spine Sarcoma on Wellbeing.Psycho-oncology · 2026Article
- The importance of social vulnerability and exclusion in cancer prognosis and survival: a scoping review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Review
- Longitudinal trajectories and predictive factors of depressive symptomatology in Chinese elderly with hearing loss: a growth mixture modeling analysis.BMC geriatrics · 2026Article
- Post-traumatic stress disorder and social determinants of health among individuals with cancer: association with healthcare utilization and outcomes in the All of Us Research Program.Journal of cancer survivorship : research and practice · 2026Article
- Synergistic effects of group-based exercise to reduce loneliness and social isolation and to prevent cognitive decline among older adults with cancer.Frontiers in aging · 2026Article
- Network Analysis of Social Anxiety, Avoidant Behavior, and Spiritual Well-Being in Breast Cancer Patients: A Pathway to Targeted Psychosocial Interventions.Depression and anxiety · 2026Article
- Social isolation to depression: the chain mediating effect of sleep duration and frailty-evidence from a Chinese nationwide cross-sectional study.BMC geriatrics · 2025Article
- Combined effects of depression and sedentary behavior on mortality risk among older adults: a population-based cohort study.BMC geriatrics · 2025Article
- The Impact of a Personal Cancer Diagnosis on the Psychological Health of Adolescent/Young Adult Cancer Survivors: A Mixed Methods Study.Psycho-oncology · 2025Article
- Factors associated with social alienation in cancer patients: a structural equation modeling approach.Frontiers in psychology · 2025Article
- Global Trends and Research Hotspots in Social Isolation Among Cancer Patients: A Bibliometric Analysis (2005-2024).Journal of multidisciplinary healthcare · 2025Review
- Burden and trends of major depressive disorders among women of childbearing age and the impact of the COVID-19 pandemic: insights from the global burden of disease study 2021.Frontiers in psychiatry · 2025Article
- Empowering pediatric, adolescent, and young adult patients with cancer utilizing generative AI chatbots to reduce psychological burden and enhance treatment engagement: a pilot study.Frontiers in digital health · 2025Article
- Young lung cancer: from diagnosis to survivorship.Frontiers in oncology · 2025Review
- Psychosocial Factors Affecting Wellbeing and Sources of Support of Young Adult Cancer Survivors: A Scoping Review.Nursing reports (Pavia, Italy) · 2024Article
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14 authors.
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Abstract
backgroundSocial isolation and social connectedness are health determinants and aspects of social well-being with strong associations with psychological distress. This study evaluated relationships among social isolation, social connectedness, and psychological distress (i.e., depression, anxiety) over 1 year in young adult (YA) cancer survivors 18-39 years old.
methodsParticipants were YAs in a large cohort study that completed questionnaires every 2 months for 1 year. Social isolation, aspects of social connectedness (i.e., companionship, emotional support, instrumental support, and informational support), depression, and anxiety were assessed with Patient-Reported Outcomes Measurement Information System short form measures. Mixed-effect models were used to evaluate changes over time. Confirmatory factor analysis and multilevel structural equation modeling were used to define social connectedness as a latent construct and determine whether relationships between social isolation and psychological distress were mediated by social connectedness.
resultsParticipants (N = 304) were mean (M) = 33.5 years old (SD = 4.7) and M = 4.5 years (SD = 3.5) post-initial cancer diagnosis. Most participants were female (67.4%) and non-Hispanic White (68.4%). Average scores for social well-being and psychological distress were within normative ranges and did not change (p values >.05). However, large proportions of participants reported at least mild social isolation (27%-30%), depressive symptoms (36%-37%), and symptoms of anxiety (49%-51%) at each time point. Across participants, more social isolation was related to less social connectedness (p values <.001), more depressive symptoms (p < .001), and more symptoms of anxiety (p < .001). Social connectedness mediated the relationship between social isolation and depression (p = .004), but not anxiety (p > .05).
conclusionsSocial isolation and connectedness could be intervention targets for reducing depression among YA cancer survivors.
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