ArticleBMJ open diabetes research & care2024
Cardiovascular disease risk factors and their associations with inflammation among US adolescents: NHANES, 2015 to March 2020.
Article in BMJ open diabetes research & care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Cardiovascular Health Was Moderate in Austrian Adolescents and Showed an Inverse Relationship With High-Sensitivity C-Reactive Protein Levels.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Article
- Association Between Neutrophil-to-Lymphocyte Ratio and Mortality Risk Among Patients With Hyperlipidemia Across Different Glycemic Status: A Longitudinal Cohort Study From NHANES 1999-2018.Reviews in cardiovascular medicine · 2026Article
- Prevalence and predictors of prediabetes/type 2 diabetes mellitus among adolescents in the United States: NHANES (2021-2023).PLOS global public health · 2026Article
- Dairy consumption and cardiovascular disease risk: a multi-level analysis with inflammatory biomarker mediation.Nutrition & metabolism · 2025Article
- Joint association of estimated glucose disposal rate and systemic inflammation response index with all-cause and cardiovascular mortality in patients with dyslipidemia: a nationwide prospective cohort study.Diabetology & metabolic syndrome · 2025Article
- Association of tooth loss with circadian syndrome in US adults: the mediated role of systemic inflammation.Clinical oral investigations · 2025Article
- Association of participant reported oral health, tooth loss, interdental cleaning and dental visits with serum CRP.Scientific reports · 2025Article
- The Pathogenic Role of C-Reactive Protein in Diabetes-Linked Unstable Atherosclerosis.International journal of molecular sciences · 2025Review
- Article
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2 authors.
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Abstract
introductionThe prevalence of obesity and glycemic dysfunction in adolescents has increased over the past several decades but less is known on how these conditions are associated with systemic inflammation in this population. This study determined the associations between cardiovascular disease (CVD) risk factors and inflammation among a nationally representative sample of US. adolescents. RESEARCH DESIGN AND
methodsCross-sectional analyses were conducted among 2693 adolescents aged 12-19 years who participated in the 2015 to March 2020 National Health and Nutrition Examination Surveys. Chronic inflammation was determined using laboratory measures for high-sensitivity C reactive protein (hs-CRP). Adjusted ORs (aOR, 95% CI) were calculated from logistic regression models to determine the association between CVD risk factors (obesity, overweight, dysglycemia, hypertension, hyperlipidemia) and elevated hs-CRP (>3.0 mg/L) while controlling for sociodemographic characteristics and other CVD risk factors.
resultsOverall, 15.3% of adolescents had elevated hs-CRP. Adolescents who were older (16-19 years vs 12-15 years), obese, had A1c ≥5.7% (≥39 mmol/mol), high total cholesterol, or low high-density lipoprotein had hs-CRP distributions that were more high risk (χ
conclusionsAmong US adolescents, obesity was strongly associated with elevated hs-CRP, a marker for future CVD risk. Given the obesity epidemic and the marked proportion with elevated CRP, concern should be given to future CVD risk in younger adults.
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