ArticleImmunity2024
The amalgam of naive CD4
Abstract read
In one paragraph
Article in Immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Functional heterogeneity and plasticity in naïve CD8 T cells drive superior effector and memory responses.The Journal of experimental medicine · 2026Article
- Calibrating T cell responsiveness through interactions with self.Nature reviews. Immunology · 2026Review
- Virus-specific memory CD4 T cells sustain long-term numerical and functional impairment following whole-body irradiation.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Whole-body irradiation causes long-term impairments in the maintenance and function of naïve CD4 T cells specific for self- and non-self-antigens.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Single-cell gene expression and TCR profiling reveal age-related differences in recent thymic emigrants.iScience · 2026Article
- Review
- Helminths as architects of trained tolerance: implications for human health.Clinical & translational immunology · 2026Review
- Resolving ScRNA-Seq Signatures of Antigen-Specific CD4bioRxiv : the preprint server for biology · 2025Article
- Functional heterogeneity and plasticity in naïve CD8 T cells drive superior effector and memory responses.bioRxiv : the preprint server for biology · 2025Article
- Notch-activated basophils support intestinal CD4Mucosal immunology · 2025Article
- Sterile production of interferons in the thymus.Journal of immunology (Baltimore, Md. : 1950) · 2025Review
- The epigenetic landscape of fate decisions in T cells.Nature immunology · 2025Review
- CD301bNature communications · 2025Article
- Th1-poised naive CD4 T cell subpopulation reflects anti-tumor immunity and autoimmune disease.Nature communications · 2025Article
- Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneity.The Journal of experimental medicine · 2024Article
Corrections and comments
- Commented on by
Authors and funding
17 authors.
Zachary EvenDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Alexandre P MeliDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Antariksh TyagiYale Center for Genome Analysis, Yale School of Medicine, West Haven, CT 06516, USA.
Aurobind VidyarthiDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Neima BriggsDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA; Department of Internal Medicine (Infectious Diseases), Yale School of Medicine, New Haven, CT 06520, USA.
Dimitri A de KouchkovskyDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Yong KongDepartment of Biostatistics, Yale School of Public Health, New Haven, CT 06520, USA.
Yaqiu WangDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Daniel A WaizmanDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Tyler A RiceDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Bony De KumarYale Center for Genome Analysis, Yale School of Medicine, West Haven, CT 06516, USA.
Xusheng WangDepartment of Genetics, Genomics and Informatics, University of Tennessee, Memphis, TN 38163, USA.
Noah W PalmDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Joe CraftDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Malay K BasuDepartment of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Sourav GhoshDepartment of Neurology, Yale School of Medicine, New Haven, CT 06520, USA; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06520, USA. Electronic address: sourav.ghosh@yale.edu.
Carla V RothlinDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06520, USA. Electronic address: carla.rothlin@yale.edu.
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MMEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9MNRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9MTRAINING IN THE PATHOGENESIS OF INFECTIOUS DISEASEST32AI007517 · NIAID · YALE UNIVERSITY · PI Jaimie Meyer, Albert C Shaw · 1997 to 2026
$6.1MTAM receptor tyrosine kinases in inflammatory boweldiseaseR01AI089824 · NIAID · YALE UNIVERSITY · PI ROTHLIN, CARLA · 2010 to 2018
$3.9MAn innate immune checkpoint in cancer immunotherapy.R01CA212376 · NCI · YALE UNIVERSITY · PI GHOSH, SOURAV, ROTHLIN, CARLA · 2017 to 2021
$3.1MNaïve T cell archetypes and anti-tumor immunityR21AI174387 · NIAID · YALE UNIVERSITY · PI GHOSH, SOURAV, ROTHLIN, CARLA · 2023 to 2024
$461kHoward Hughes Medical InstituteNCATS NIH HHS TL1 TR001864NCATS NIH HHS UL1 TR001863NCI NIH HHS R01 CA212376NIAID NIH HHS R01 AI089824NIAID NIH HHS R21 AI174387NIAID NIH HHS T32 AI007517NIGMS NIH HHS T32 GM007205
Abstract
Naive CD4
Indexed as
CD4-Positive T-LymphocytesNippostrongylusAnimalsHelminthiasisInterferon Type ILymphocyte ActivationMiceMice, Inbred C57BLReceptors, Antigen, T-CellSpecific Pathogen-Free OrganismsStrongylida InfectionsTranscription, GeneticInterferon Type IReceptors, Antigen, T-Cellcommensal microbiotahelminthnaive T cellT cellstranscriptional heterogeneityvaccines
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.