Evidence map›Paper›PMID 39096375›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2025

Sexual dysfunction in dichlorvos-exposed male Wistar rat is ameliorated by curcumin and associated with the upregulation of testosterone.

W A Saka, A A Oladipo, O R Kolawole, A Olayioye, R E Akhigbe

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Endocrine Disrupting Agents: Toxicological Aspects on Male Reproduction.Reproductive sciences (Thousand Oaks, Calif.) · 2025
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

W A SakaDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria. wsaka@lautech.edu.ng.
A A OladipoDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
O R KolawoleDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
A OlayioyeDepartment of Crop and Environmental Protection, Faculty of Agricultural Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
R E AkhigbeDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dichlorvos is an organophosphate pesticide that is commonly used for agricultural and domestic control of pests and insects. Despite its usefulness, it exerts reproductive toxicity and induces male sexual dysfunction. On the other hand, curcumin has been reported to improve sexual dysfunction. However, till date, no study has reported the impact of curcumin on dichlorvos-induced sexual dysfunction. This study investigated the effect and associated mechanism of curcumin on dichlorvos-induced sexual dysfunction. Thirty-two male Wistar rats were randomized into four groups; the control (1 mL of olive oil), curcumin-treated (100 mg/kg), DDVP-treated (98.54 g/m

Indexed as

CurcuminDichlorvosInsecticidesSexual Dysfunction, PhysiologicalTestosteroneAnimalsLuteinizing HormoneMaleRatsRats, WistarSexual Behavior, AnimalTestisUp-RegulationCurcuminDichlorvosInsecticidesLuteinizing HormoneTestosteroneAphrodisiacCurcuminDichlorvosMale infertilityOrganophosphateSexual dysfunction

Identifiers

PMID39096375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.