Evidence map›Paper›PMID 39096298›Full record

ArticleACS synthetic biology2024

Optimizing Archaeal Lipid Biosynthesis in

Mirthe Hoekzema, Jiayi Jiang, Arnold J M Driessen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS synthetic biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mirthe HoekzemaDepartment of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747AG Groningen, Netherlands.
Jiayi JiangDepartment of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747AG Groningen, Netherlands.
Arnold J M DriessenDepartment of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747AG Groningen, Netherlands.ORCID 0000-0001-9258-9104

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membrane lipid chemistry is remarkably different in archaea compared with bacteria and eukaryotes. In the evolutionary context, this is also termed the lipid divide and is reflected by distinct biosynthetic pathways. Contemporary organisms have almost without exception only one type of membrane lipid. During early membrane evolution, mixed membrane stages likely occurred, and it was hypothesized that the instability of such mixtures was the driving force for the lipid divide. To examine the compatibility between archaeal and bacterial lipids, the bacterium

Indexed as

Escherichia coliArchaeaCardiolipinsCDPdiacylglycerol-Serine O-PhosphatidyltransferaseHemiterpenesMembrane LipidsMembrane ProteinsMetabolic EngineeringOrganophosphorus CompoundsPhospholipidsTerpenesTransferases (Other Substituted Phosphate Groups)Cardiolipinscardiolipin synthetaseCDPdiacylglycerol-Serine O-PhosphatidyltransferaseHemiterpenesisopentenyl pyrophosphateMembrane LipidsMembrane ProteinsOrganophosphorus CompoundsPhospholipidsTerpenesTransferases (Other Substituted Phosphate Groups)hybrid membranesIUPlipid biosynthesislipid dividesynthetic isoprenoid utilization pathway

Identifiers

PMID39096298
PMCPMC11334171

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.