Evidence map›Paper›PMID 39096118›Full record

SynthesisCancer medicine2024

Participant factors associated with psychosocial impacts of lung cancer screening: A systematic review.

Kathleen McFadden, Brooke Nickel, Nicole M Rankin, Tong Li, Chloe J Jennett, Ashleigh Sharman, Samantha L Quaife, Nehmat Houssami, Rachael H Dodd

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kathleen McFaddenThe Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, Australia.ORCID 0000-0003-1546-8901
Brooke NickelSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Nicole M RankinSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Tong LiThe Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, Australia.ORCID 0000-0003-4956-765X
Chloe J JennettThe Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, Australia.
Ashleigh SharmanSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.ORCID 0000-0002-9342-5061
Samantha L QuaifeWolfson Institute of Population Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Nehmat HoussamiThe Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, Australia.
Rachael H DoddThe Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, Australia.

Funding

Barts Charity programme grant G-001522Barts Charity programme grant MGU0461Cancer Institute NSW Early Career Fellowship #2022/ECF1420National Breast Cancer Foundation (NBCF) Chair in Breast Cancer Prevention grant EC-21-001National Health and Medical Research Council Investigator (Emerging Leader) Research Fellowship 1194108National Health and Medical Research Council Investigator (Leader) grant 1194410The Daffodil Centre Postgraduate Research Scholarship
6 · The paper itself

Abstract

backgroundPsychosocial impacts of lung cancer screening (LCS) can cause both harm to individuals and serve as barriers to screening participation and adherence. Early data suggest that the psychosocial impacts of LCS are moderated by certain factors (e.g. sociodemographic characteristics and beliefs), but evidence synthesis is lacking. This systematic review aimed to understand individual-level risk factors for psychosocial burden during LCS as a precursor to developing strategies to identify and support participants, and improve LCS engagement.

methodsFour databases were searched for full-text articles published in English reporting any association between participant factors and psychosocial outcomes experienced during LCS. Study quality was assessed by two independent investigators; findings were synthesised narratively. The review was pre-registered with PROSPERO and adhered to PRISMA guidelines.

resultsThirty-five articles were included; most (33/35) studies were assessed at high or moderate risk of bias. Study designs were pre-post (n = 13), cross-sectional (n = 13), qualitative (n = 8) and mixed-methods (n = 1) and conducted primarily in the United States (n = 17). Psychological burden in LCS varied, and was often associated with younger age, female gender, current smoking status or increased smoking history, lower education, lower socio-economic group, not being married or co-habiting and experience with cancer. However, results were mixed, and non-significant associations were also reported across all factors. Beliefs (e.g. fatalism, stigma and expectation of LDCT results) and comorbid psychological burden were also linked to psychosocial outcomes, but evidence was sparse. Associations between risk perception, other participant factors and other psychosocial outcomes was inconclusive, likely reflecting individual biases in risk conceptualisation. CONCLUSION(S): Several participant factors are consistently reported to be associated with psychosocial impacts of LCS, though study heterogeneity and high risk of bias necessitate more robust evaluation. Further research on how perceptions, beliefs and expectations can be used to improve psychosocial outcomes during LCS is needed.

Indexed as

Early Detection of CancerLung NeoplasmsFemaleHumansMaleRisk Factors

Identifiers

PMID39096118
PMCPMC11297455

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.