ArticleAnnals of general psychiatry2024
Global, regional, and national time trends in incidence for depressive disorders, from 1990 to 2019: an age-period-cohort analysis for the GBD 2019.
Article in Annals of general psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The research progress on effective connectivity in adolescent depression based on resting-state fMRI.Frontiers in neurology · 2025Pooled it
- Prevalence and correlates of depression among older persons in rural eastern Uganda: a cross-sectional survey.Global health action · 2026Article
- Therapeutic Potential of Nanocurcumin in Mitigating Duloxetine-Induced Hepatic Damage: Biochemical and Histopathological Insights.Journal of biochemical and molecular toxicology · 2026Article
- Technical system of electroencephalography-based brain-computer interface: Advances, applications, and challenges.Neural regeneration research · 2026Article
- Sugar-sweetened beverage consumption and incident depression: an exploratory multi-omics analysis of candidate biological mediators.Nutrition journal · 2026Article
- GATA1 repression-mediated ADRB2/cAMP/PKA signaling activation underlies the antidepressant effects of targeted geniposide delivery.Cell death discovery · 2026Article
- Micro- and Nanoplastics in the Human Brain: Mechanistic Plausibility, Translational Challenges, and Links to Neurological Disease Trends.Molecular neurobiology · 2026Review
- Nonlinear threshold and association of depressive symptoms with pain in middle-aged and older Chinese adults: a cross-sectional and cohort study.Scientific reports · 2026Article
- Red blood cell folate and depression risk in U.S. women: A dose-response analysis from a nationwide cross-sectional study (2009-2018).Medicine · 2026Article
- Temporal trends in late-life depressive symptom trajectories: a longitudinal population-based cohort study from Stockholm, Sweden.BMJ public health · 2026Article
- Development and External Validation of a Prediction Model to Identify Suicide Attempters in Treatment-Naive Adolescents With Major Depressive Disorder.Depression and anxiety · 2026Article
- Obesity and Depression: A Pathophysiotoxic Relationship.International journal of molecular sciences · 2025Review
- Association between body roundness index and trajectories of depressive symptoms among Chinese middle-aged and older adults: a nationwide cohort study from CHARLS.BMC psychology · 2025Article
- Global Burden of Depressive Disorders, 1990-2021, During the COVID-19 Pandemic and Projections to 2050: A Global Burden of Disease Study 2021.Psychiatry investigation · 2025Article
- Epidemiological trends and age-period-cohort effects on urolithiasis incidence across the BRICS-plus from 1992 to 2021.BMC nephrology · 2025Article
- Early-Life famine exposure and the risk of depression and anxiety in adulthood: evidence from the China Multi-Ethnic Cohort (CMEC).BMC psychiatry · 2025Article
- Chronic neck pain as an exacerbating factor for depressive symptoms in a 1-Year longitudinal population study.Scientific reports · 2025Article
- Impact of temperature variations on burden of lower respiratory infections under climate change (1990-2021).BMC public health · 2025Article
- The Association Between Hearing Loss and Depression in a Large Electronic Health Record System.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Mind matters: a comparative study of self-reported severity of depression and cognitive symptoms in China and the USA.BMC public health · 2025Article
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16 authors.
Funding
Abstract
backgroundEven with advances in primary health care, depressive disorders remain a major global public health problem. We conducted an in-depth analysis of global, regional and national trends in depressive disorders incidence over the past 30 years.
methodsData on the incidence of depressive disorders were obtained by sex (female, male, and both), location (204 countries), age (5-84 years), year (1990-2019) from the Global Burden of Disease Study (GBD) 2019. Further, age-period-cohort modeling was used to estimate the net drift, local drift, age, period and cohort effects between 1990 and 2019.
resultsIn 2019, although the incidence of depressive disorders has increased by 59.3% to 290 million (95% UI: 256, 328), the age-standardized incidence rate has decreased by 2.35% to 3588.25 per 100,000 people (3152.71, 4060.42) compared to 1990. There was an emerging transition of incidences from the young and middle-aged population to the old population. From 1990 to 2019, the net drift of incidence rate ranged from -0.54% (-0.61%, -0.47%) in low-middle Socio-demographic Index (SDI) regions to 0.52% (0.25%, 0.79%) in high SDI regions. Globally, the incidence rate of depressive disorders increases with age, period effects showing a decreasing risk and cohort effects beginning to decline after the 1960s.
conclusionsOur current findings reflect substantial health disparities and potential priority-setting of depressive disorders incidence in the three dimensions of age, period and cohort across SDI regions, countries. The scope of healthcare to improve the progression of depressive disorders events can be expanded to include males, females of all ages.
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