SynthesisBMC infectious diseases2024
Mortality and associated factors among patients with TB-HIV co-infection in Ethiopia: a systematic review and meta-analysis.
Synthesis in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Differences in tuberculosis prevalence by sex in low- and middle-income countries over 1993-2025: A systematic review and meta-analysis.PLoS medicine · 2026Pooled it
- Mortality and associated factors among children with the double burden of human immunodeficiency virus and tuberculosis in African countries: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Meta-analysis of TB & HIV co-infection mortality rate in sub-Saharan African children, youth, and adolescents.Italian journal of pediatrics · 2025Pooled it
- Epidemiological, Spatial and Predictive Analysis of Tuberculosis-Related Mortality in the Department of Risaralda (Colombia), 2020-2024.Tropical medicine & international health : TM & IH · 2026Observational
- Survival and risk factors of mortality among patients with TB/HIV coinfection in Kigali City, Rwanda: a retrospective cohort study (2019-2024).BMC infectious diseases · 2026Article
- Adaptation of a Smartphone-Based Mobile Health Program to Support Person-Centered Treatment of Tuberculosis in Kilimanjaro, Tanzania: Preimplementation Qualitative Needs Assessment.JMIR formative research · 2026Article
- Effect of BMI on Mortality in Patients With Tuberculosis and HIV Coinfection in Asia and Africa: Systematic Review and Meta-Analysis.Asian/Pacific Island nursing journal · 2026Review
- Treatment outcomes among tuberculosis patients with co-morbidities at Ghana's premier national referral centre: a retrospective cross-sectional study.BMC infectious diseases · 2026Article
- Knowledge and prevention practices regarding cytomegalovirus among pregnant women in Gondar city a multicenter cross-sectional study.Scientific reports · 2026Article
- Mortality and associated factors among PLHIV admitted in selected hospitals in Ethiopia: A Cross-sectional Study.BMC infectious diseases · 2025Article
- Exploring the Gender Preferences for Healthcare Providers and Their Influence on Patient Satisfaction.Healthcare (Basel, Switzerland) · 2025Article
- A mixed-methods study on healthcare workers' perceptions of treatment adherence among HIV-TB co-infected patients in a multi-disease prevention policy context.Frontiers in public health · 2025Article
- BALF metagenomic next-generation sequencing for the diagnosis of pulmonary mycobacterial infection in persons with HIV: a retrospective, diagnostic accuracy study.Frontiers in microbiology · 2025Article
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2 authors.
Funding
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Abstract
backgroundTuberculosis (TB) and human immunodeficiency virus (HIV) co-infection is a major public health problem in Ethiopia. Patients with TB-HIV co-infection have significantly higher mortality rates compared to those with TB or HIV mono-infection. This systematic review and meta-analysis aim to summarize the evidence on mortality and associated factors among patients with TB-HIV co-infection in Ethiopia.
methodsComprehensive searches were conducted in multiple electronic databases (PubMed/MEDLINE, Embase, CINAHL, Web of Science) for observational studies published between January 2000 and present, reporting mortality rates among TB/HIV co-infected individuals. Two reviewers performed study selection, data extraction, and quality assessment independently. Random-effects meta-analysis was used to pool mortality estimates, and heterogeneity was assessed using I² statistics. Subgroup analyses and meta-regression were performed to explore potential sources of heterogeneity.
results185 articles were retrieved with 20 studies included in the final analysis involving 8,113 participants. The pooled mortality prevalence was 16.65% (95% CI 12.57%-19.65%) with I
conclusionsTB/HIV co-infected patients in Ethiopia experience unacceptably high mortality, driven by clinical markers of advanced immunosuppression. Early screening, timely treatment initiation, optimizing preventive therapies, and comprehensive management of comorbidities are imperative to improve outcomes in this vulnerable population.
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