Evidence map›Paper›PMID 39095735›Full record

Trial reportBMC cancer2024

'Just because I have prostate cancer doesn't mean that I can't do things' - men's experiences of the acceptability of an exercise intervention for prostate cancer during treatment.

Kira Murphy, Bróna Kehoe, Suzanne Denieffe, Aisling McGrath, Dayle Hacking, Ciaran M Fairman, Michael Harrison

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05156424 (A Comparison of Aerobic and Resistance Exercise for Counteracting the Adverse Effects of Androgen Deprivation Therapy in Men With Prostate Cancer), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05156424 phase1 / phase2unknown statusnot on this map

A Comparison of Aerobic and Resistance Exercise for Counteracting the Adverse Effects of Androgen Deprivation Therapy in Men With Prostate Cancer

TypeinterventionalSponsorKira MurphyRan2021 to 2023Enrolled24ConditionsExercise, Prostate CancerArmsExercise
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A systematic review of patient and healthcare professional perceptions of the barriers and facilitators to embedding exercise in the adjuvant cancer treatment pathway.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Article
  3. Qualitative research exploring the complexities of exercise promotion in prostate cancer survivorship.International journal of qualitative studies on health and well-being · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kira MurphyDepartment of Sport and Exercise Science, South East Technological University, Cork Rd., Waterford, Ireland.
Bróna KehoeDepartment of Sport and Exercise Science, South East Technological University, Cork Rd., Waterford, Ireland.
Suzanne DenieffeSchool of Humanities, South East Technological University, Waterford, Ireland.
Aisling McGrathDepartment of Sport and Exercise Science, South East Technological University, Cork Rd., Waterford, Ireland.
Dayle HackingUPMC Hillman Cancer Center, Whitfield Hospital, Waterford, Ireland.
Ciaran M FairmanDepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Michael HarrisonDepartment of Sport and Exercise Science, South East Technological University, Cork Rd., Waterford, Ireland. Michael.Harrison@setu.ie.

Funding

Irish Research Council EBPPG/2020/103UPMC Hillman Cancer Center, Whitfield Hospital EBPPG/2020/103
6 · The paper itself

Abstract

backgroundStructured exercise has an important role in mitigating the extensive side effects caused by ongoing prostate cancer treatments, specifically androgen deprivation therapy (ADT) and radiation therapy (RT). Little is known about men's experiences of, and preferences for, structured exercise programmes during active cancer treatment. This study aimed to inform the acceptability of a 6-month supervised intervention that emphasised increasing and varied intensities of aerobic and resistance exercise, by exploring the experiences of men who participated.

methodsIndividual semi-structured interviews were conducted with an interviewer independent of the exercise study and data was analysed using a descriptive qualitative design.

resultsTwelve prostate cancer patients were interviewed including participants who completed (n = 9) and withdrew from (n = 3) the intervention. Four main themes captured how men experienced the intervention: (1) Navigating the Unknown: Building confidence amidst vulnerability (subtheme- pushing the limits), (2) Building Trust: The credibility and approach of the exercise instructor (subtheme- appropriateness of supervised vs. independent exercise), (3) Flexibility in Delivery, (4) Finding Purpose: Exercise as a means of escapism and regaining control during treatment.

conclusionWhile an initial lack of self-confidence can be a barrier to exercise participation, exercise programmes have the potential to provide psychosocial benefits, rebuild confidence and empower men throughout their cancer treatment and into recovery. Structured exercise is acceptable during treatment including RT and can offer a form of escapism and sense of control for men navigating their cancer journey. Trust building, flexible delivery and credibility alongside a challenging exercise prescription are important facilitators of acceptability for men. Strategies to embed exercise from the point of diagnosis through ADT and RT should reflect men's experiences of exercise during treatment.

trial registrationThe trial has been registered on ClinicalTrials.gov as of the 14th of December 2021 (NCT05156424).

Indexed as

Exercise TherapyProstatic NeoplasmsAgedAged, 80 and overAndrogen AntagonistsExerciseHumansMaleMiddle AgedPatient Acceptance of Health CareQualitative ResearchAndrogen AntagonistsCancer treatmentConfidenceExercise instructorExercise oncologyRadiation therapy

Identifiers

PMID39095735
PMCPMC11297682

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.