ArticleBMC genomics2024
Spatial transcriptome reveals the region-specific genes and pathways regulated by Satb2 in neocortical development.
Article in BMC genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed.
- Spatially multimodal and multiscale network for representation learning from spatial multi-omics.BMC genomics · 2026Article
- SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- BrainConnect: processing brain connectivity and spatial transcriptomics data for integrative analysis.Bioinformatics (Oxford, England) · 2026Article
- Maternal Poly (I:C)-Induced Placental Inflammation and Endocrine Dysfunction Are Associated with Disrupted Corticogenesis in Mouse Offspring.Brain sciences · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundIt is known that the neurodevelopmental disorder associated gene, Satb2, plays important roles in determining the upper layer neuron specification. However, it is not well known how this gene regulates other neocortical regions during the development. It is also lack of comprehensive delineation of its spatially regulatory pathways in neocortical development.
resultsIn this work, we utilized spatial transcriptomics and immuno-staining to systematically investigate the region-specific gene regulation of Satb2 by comparing the Satb2
conclusionsIn summary, our work provides insights on the region-specific genes and pathways which are regulated by Satb2 in neocortical development.
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Registered trials
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