Evidence map›Paper›PMID 39095685›Full record

ArticleBioresources and bioprocessing2024

Enhancement of astaxanthin accumulation via energy reassignment by removing the flagella of Haematococcus pluvialis.

Yuyong Hou, Zhile Guo, Zhiyong Liu, Suihao Yan, Meijie Cui, Fangjian Chen, Weijie Wang, Longjiang Yu, Lei Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioresources and bioprocessing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Astaxanthin fromMarine drugs · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuyong Hou *College of Life Science, North China University of Science and Technology, Tangshan, China.
Zhile Guo *College of Life Science, North China University of Science and Technology, Tangshan, China.
Zhiyong LiuKey Laboratory of Engineering Biology for Low-carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.
Suihao YanKey Laboratory of Engineering Biology for Low-carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.
Meijie CuiKey Laboratory of Engineering Biology for Low-carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.
Fangjian ChenKey Laboratory of Engineering Biology for Low-carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.
Weijie WangCollege of Life Science, North China University of Science and Technology, Tangshan, China. weijiewang@ncst.edu.cn.
Longjiang YuPhotosynthesis Research Center, Key Laboratory of Photobiology, Institute of Botany, Chinese Academy of Sciences, Beijing, China. longer@ibcas.ac.cn.
Lei ZhaoCollege of Life Science, North China University of Science and Technology, Tangshan, China. zhaol@tib.cas.cn.

Funding

Hundred Talents Program of the Chinese Academy of Sciences E3J56201National Key R&D Program of China 2022YFC3401803Science and Technology Partnership Program, Ministry of Science and Technology of China KY202001017Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project TSBICIP-IJCP-001; TSBICIP-CXRC-027
6 · The paper itself

Abstract

Astaxanthin biosynthesis in Haematococcus pluvialis is driven by energy. However, the effect of the flagella-mediated energy-consuming movement process on astaxanthin accumulation has not been well studied. In this study, the profiles of astaxanthin and NADPH contents in combination with the photosynthetic parameters with or without flagella enabled by pH shock were characterized. The results demonstrated that there was no significant alteration in cell morphology, with the exception of the loss of flagella observed in the pH shock treatment group. In contrast, the astaxanthin content in the flagella removal groups was 62.9%, 62.8% and 91.1% higher than that of the control at 4, 8 and 12 h, respectively. Simultaneously, the increased Y(II) and decreased Y(NO) suggest that cells lacking the flagellar movement process may allocate more energy towards astaxanthin biosynthesis. This finding was verified by NADPH analysis, which revealed higher levels in flagella removal cells. These results provide preliminary insights into the underlying mechanism of astaxanthin accumulation enabled by energy reassignment in movement-lacking cells.

Indexed as

AstaxanthinEnergy flowFlagellaHaematococcus pluvialispH-shock

Identifiers

PMID39095685
PMCPMC11296984

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.