ArticleScientific data2024
Telomere-to-telomere genome assembly of sorghum.
Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- The first telomere-to-telomere genome assembly of the soybean male-sterile germplasm 88-428BY by massive parallel sequencing.Plant diversity · 2026Article
- A highly contiguous chromosome-level genome assembly of the Chilean jack mackerel Trachurus murphyi.Scientific data · 2026Article
- Nanopore Data-Driven Near-T2T Genome Assembly ofPlants (Basel, Switzerland) · 2026Article
- Improved Visualization Method of DNA Sequences and its Application in Phylogenetic Analysis.Combinatorial chemistry & high throughput screening · 2026Article
- A telomere-to-telomere genome assembly of Chinese grain sorghum 654.Scientific data · 2025Article
- Telomere-to-telomere genome of common bean (Phaseolus vulgaris L., YP4).GigaScience · 2025Article
- A telomere-to-telomere genome assembly of koi carp (Cyprinus carpio) using long reads and Hi-C technology.GigaScience · 2025Article
- The complete genome assembly of Astragalus membranaceus: enabling more accurate genetic research.GigaScience · 2025Article
- Advances in Whole Genome Sequencing: Methods, Tools, and Applications in Population Genomics.International journal of molecular sciences · 2025Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
"Cuohu Bazi" (CHBZ) is an ancient sorghum variety collected from the fields of China, known for its agronomic traits like dwarf stature, early maturation. In this study, we present the first telomere-to-telomere (T2T) and gap-free genome assembly of CHBZ using PacBio HiFi reads, Oxford Nanopore Technologies, and Hi-C data. The assembled genome comprises 724.85 Mb, effectively resolving all 3,913 gaps that were present in the previous sorghum BTx623 reference genome. Notably, the T2T assembly captures 10 centromeres and all 20 telomeres, providing strong support for their integrity. This assembly is of high quality in terms of contiguity (contig N50: 71.1 Mb), completeness (BUSCO score: 99.01%, k-mer completeness: 98.88%), and correctness (QV: 61.60). Repetitive sequences accounted for 70.41% of the genome and a total of 32,855 protein-coding genes have been annotated. Furthermore, 161 CHBZ-specific presence/absence variants genes have been identified when comparing to BTx623 genome. This study provides valuable insights for future research on sorghum genetics, genomics, and evolutionary history.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.