Evidence map›Paper›PMID 39095342›Full record

ArticleNutrition & diabetes2024

Flavor and taste recognition impairments in people with type 1 diabetes.

Immacolata Cristina Nettore, Giuseppe Palatucci, Paola Ungaro, Giuseppe Scidà, Alessandra Corrado, Rosa De Vito, Marilena Vitale, Anna Maria Rivieccio, Giovanni Annuzzi, Lutgarda Bozzetto and 2 more

Abstract read
In one paragraph

Article in Nutrition & diabetes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Immacolata Cristina Nettore *Dipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy.
Giuseppe Palatucci *Dipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy.
Paola UngaroIstituto per l'Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy.
Giuseppe ScidàDipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy.ORCID 0000-0002-8095-0799
Alessandra CorradoDipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy.
Rosa De VitoDipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy.
Marilena VitaleDipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy.
Anna Maria RivieccioDipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy.
Giovanni AnnuzziDipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy.
Lutgarda BozzettoDipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy.
Annamaria ColaoDipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy.
Paolo Emidio MacchiaDipartimento di Medicina Clinica e Chirurgia, Scuola di Medicina, Università degli Studi di Napoli Federico II, Naples, Italy. pmacchia@unina.it.ORCID 0000-0001-6503-6942

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca (Ministry of Education, University and Research) 20173CRP3H_002
6 · The paper itself

Abstract

BACKGROUND/

objectivesAdherence to dietary recommendations is a critical component in the management of type 1 diabetes (T1D). Taste and flavor significantly influence food choices. The aim of this study was to investigate taste sensitivity and flavor recognition ability in adults with T1D compared to healthy individuals. SUBJECTS/

methodsSeventy-two people with T1D and 72 matched healthy controls participated in the study. Participants underwent the gustometry test for sweet, sour, salty, and bitter tastes and the flavor test, which consisted of oral administration of aqueous aromatic solutions identifying 21 different compounds.

resultsParticipants with T1D had significantly lower flavor scores and gustometry scores than controls (p < 0.0001 and p = 0.0063, respectively). T1D individuals showed a lower perception of sour, bitter and salty tastes than controls, while the perception of sweet taste was similar. The sex differences and age-related decline in flavor perception observed in controls were not present in the participants with T1D. Neither BMI nor disease-related parameters such as fasting blood glucose on the day of the study, glycosylated hemoglobin, age at onset of diabetes, duration of diabetes, or type of insulin treatment (insulin pump or multiple daily injections) correlated with flavor and taste perception in the T1D participants.

conclusionsFlavor and taste perception are impaired in adults with T1D, potentially affecting dietary adherence and food choices. This highlights the need for further research into the mechanisms underlying sensory changes in T1D and emphasizes the importance of targeted dietary interventions to improve health outcomes and quality of life in this population.

Indexed as

Diabetes Mellitus, Type 1TasteTaste PerceptionAdultBlood GlucoseCase-Control StudiesFemaleFood PreferencesGlycated HemoglobinHumansInsulinMaleMiddle AgedYoung AdultBlood GlucoseGlycated HemoglobinInsulin

Identifiers

PMID39095342
PMCPMC11297142

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.