ArticleJornal brasileiro de nefrologia
Growth in children with chronic kidney disease and associated risk factors for short stature.
Article in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Evidence-Based Guidelines for the Diagnosis and Treatment of Pediatric CKD-Mineral and Bone Disorder (Version 2024).Kidney international reports · 2026Article
- Dietary phosphate exposure-strategies to protect vulnerable population groups.Archives of toxicology · 2026Review
- Establishment of reference ranges and stability assessment for target height completion rate based on the China Health and Nutrition Survey (CHNS).Frontiers in public health · 2026Article
- Short stature-related factors and nomogram-based risk prediction in children aged 7-12: evidence from Chaozhou, China.Frontiers in endocrinology · 2026Article
- Just a consequence of hunger or a sign of chronic kidney disease in children? The dilemma of growth failure in countries with regional disparities.Jornal brasileiro de nefrologiaArticle
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9 authors.
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Abstract
introductionGrowth failure in chronic kidney disease is related to high morbidity and mortality. Growth retardation in this disease is multifactorial. Knowing the modifiable factors and establishing strategies to improve care for affected children is paramount.
objectivesTo describe growth patterns in children with chronic kidney disease and the risk factors associated with short stature.
methodsWe retrospectively analyzed anthropometric and epidemiological data, birth weight, prematurity, and bicarbonate, hemoglobin, calcium, phosphate, alkaline phosphatase, and parathormone levels of children with stages 3-5 CKD not on dialysis, followed for at least one year.
resultsWe included 43 children, the majority of which were boys (65%). The mean height/length /age z-score of the children at the beginning and follow-up was -1.89 ± 1.84 and -2.4 ± 1.67, respectively (p = 0.011). Fifty-one percent of the children had short stature, and these children were younger than those with adequate stature (p = 0.027). PTH levels at the beginning of the follow-up correlated with height/length/age z-score. A sub-analysis with children under five (n = 17) showed that 10 (58.8%) of them failed to thrive and had a lower weight/age z-score (0.031) and lower BMI/age z-score (p = 0.047).
conclusionChildren, particularly younger ones, with chronic kidney disease who were not on dialysis had a high prevalence of short stature. PTH levels were correlated with height z-score, and growth failure was associated with worse nutritional status. Therefore, it is essential to monitor the growth of these children, control hyperparathyroidism, and provide nutritional support.
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