Evidence map›Paper›PMID 39093494›Full record

ArticleNeurosurgical review2024

Influence of an improvement in frontal lobe hemodynamics on neurocognitive function in adult patients with moyamoya disease.

Sho Tsunoda, Tomohiro Inoue, Kazuhiro Ohwaki, Naoko Takeuchi, Takako Shinkai, Akira Fukuda, Masafumi Segawa, Mariko Kawashima, Atsuya Akabane, Satoru Miyawaki and 1 more

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Article in Neurosurgical review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sho TsunodaDepartment of Neurosurgery, NTT Medical Center Tokyo, 5-9-22, Higashigotanda, Shinagawa-Ku, Tokyo, 141-0022, Japan. s.tsunoda1024@gmail.com.ORCID http://orcid.org/0000-0001-9217-8575
Tomohiro InoueDepartment of Neurosurgery, NTT Medical Center Tokyo, 5-9-22, Higashigotanda, Shinagawa-Ku, Tokyo, 141-0022, Japan.
Kazuhiro OhwakiTeikyo University Graduate School of Public Health, Kaga, Itabashi-Ku, Tokyo, Japan.
Naoko TakeuchiDepartment of Rehabilitation, NTT Medical Center Tokyo, Higashigotanda, Shinagawa-Ku, Tokyo, Japan.
Takako ShinkaiDepartment of Rehabilitation, NTT Medical Center Tokyo, Higashigotanda, Shinagawa-Ku, Tokyo, Japan.
Akira FukudaDepartment of Rehabilitation, NTT Medical Center Tokyo, Higashigotanda, Shinagawa-Ku, Tokyo, Japan.
Masafumi SegawaDepartment of Neurosurgery, NTT Medical Center Tokyo, 5-9-22, Higashigotanda, Shinagawa-Ku, Tokyo, 141-0022, Japan.
Mariko KawashimaDepartment of Neurosurgery, NTT Medical Center Tokyo, 5-9-22, Higashigotanda, Shinagawa-Ku, Tokyo, 141-0022, Japan.
Atsuya AkabaneDepartment of Neurosurgery, NTT Medical Center Tokyo, 5-9-22, Higashigotanda, Shinagawa-Ku, Tokyo, 141-0022, Japan.
Satoru MiyawakiDepartment of Neurosurgery, The University of Tokyo Hospital, Hongo, Bunkyo-Ku, Tokyo, Japan.
Nobuhito SaitoDepartment of Neurosurgery, The University of Tokyo Hospital, Hongo, Bunkyo-Ku, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn adults, moyamoya disease (MMD) often presents with slight neurocognitive impairment, which may result from frontal lobe hemodynamic insufficiency.

methodsIn this study, we performed revascularization surgery by superficial temporal artery-anterior cerebral artery (ACA) direct bypass in 20 adults with MMD with poor anterograde ACA flow (Group M). The pre- and postoperative neurocognitive test results of these patients were retrospectively analyzed. The comparative group (Group C) included 23 patients with unruptured aneurysms or brain tumors who underwent craniotomy, as well as the same neurocognitive tests as Group M. We calculated the compositive frontal lobe function index (CFFI) based on the results of seven neurocognitive tests for each patient, and the difference between the pre- and postoperative CFFI values (CFFI Post - Pre) was compared between the two groups.

resultsFrontal perfusion improved postoperatively in all patients in Group M. The CFFI Post - Pre was significantly higher in Group M than in Group C (0.23 ± 0.44 vs. - 0.20 ± 0.32; p < 0.001). After adjusting for postoperative age, sex, preoperative non-verbal intelligence quotient, and preoperative period of stress, Group M had a significantly higher CFFI Post - Pre than Group C in the multiple regression analysis (t value = 4.01; p < 0.001).

conclusionImproving frontal lobe hemodynamics might be the key for improving neurocognitive dysfunction in adults with MMD. The surgical indication and method should be considered from the perspective of both stroke prevention and neurocognitive improvement or protection.

Indexed as

Cerebral RevascularizationFrontal LobeHemodynamicsMoyamoya DiseaseNeuropsychological TestsAdultAnterior Cerebral ArteryCerebrovascular CirculationFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeYoung AdultAnterior cerebral arteryBypassFrontal lobeHemodynamic insufficiencyMoyamoya diseaseNeurocognitive functionRevascularization

Identifiers

PMID39093494

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.