Evidence map›Paper›PMID 39093425›Full record

ArticleSkeletal radiology2025

Pseudoendocrine sarcoma: a rare new entity with unique radiologic and pathologic/molecular characteristics.

Zachary Corey, Julie C Fanburg-Smith, Cristy N French, Eric A Walker, Harry N Kamerow, Eric L Cochran, Jessica D Smith, Donald J Flemming, Mark D Murphey

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PubMed Full text at PMC Publisher
In one paragraph

Article in Skeletal radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zachary CoreyUCHealth at University of Colorado Anschutz Medical, Aurora, CO, USA.
Julie C Fanburg-SmithDepartment of Pathology and Pediatrics, UVA Health University of Virginia Medical Center, Charlottesville, VA, 22903, USA. jcfsmd@gmail.com.ORCID http://orcid.org/0000-0002-5404-096X
Cristy N FrenchDepartment of Radiology, Penn State Health, Hershey, PA, 17033, USA.
Eric A WalkerDepartment of Radiology, Penn State Health, Hershey, PA, 17033, USA.
Harry N KamerowMount Nittany Medical Center, State College, PA, 16803, USA.
Eric L CochranDepartment of Pathology, Penn State Health, Hershey, PA, 17033, USA.
Jessica D SmithMSII WVSOM, Lewisburg, WV, 24901, USA.
Donald J FlemmingRadiology Department, University of Kentucky College of Medicine, Lexington, KY, 40546, USA.
Mark D MurpheyACR - Institute for Radiologic Pathology (AIRP), Silver Spring, MD, 20910, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudoendocrine sarcoma is a rare, recently described intermediate grade sarcoma of uncertain phenotype that most commonly affects the paraspinal location in older patients with a distinctive endocrine/paraganglioma-like morphology and unique CTNNB1 point mutation. While these tumors appear as epithelial or even benign endocrine tumors, these lack markers for such and are highlighted by nuclear expression of beta-catenin. This case is the first among the previously reported only twenty-five cases of this entity, including one original series and a few case reports, to correlate the radiologic imaging with the pathologic features. Furthermore, this case illustrates the oldest-to-date patient with this unique location as a palpable painful chest wall/paraspinal location, with new morphologic observations and, finally, this is only the second case to have this specific CTNNB1 hotspot point mutation for this rare entity.

Indexed as

beta CateninSarcomaDiagnosis, DifferentialFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPoint Mutationbeta CateninCTNNB1 protein, humanCTNNB1 point mutationDiagnosisPathologic vascularity/zellballen patternPseudoendocrine sarcomaRadiologic feeder vesselsRare new entity

Identifiers

PMID39093425
PMCPMC11953146

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.