ArticleIn vitro cellular & developmental biology. Animal2025
Novel use of a - 20°C cryoprotectant yields high viability and improved aggregation of marine sponge cells.
Elizabeth Urban-Gedamke, Megan Conkling, Cynthia Goodman, Xu Han, Shirley A Pomponi
Abstract read
In one paragraphArticle in In vitro cellular & developmental biology. Animal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
5 authors.
Elizabeth Urban-GedamkeHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US 1 North, Fort Pierce, FL, 34946, USA.
Megan ConklingHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US 1 North, Fort Pierce, FL, 34946, USA.
Cynthia GoodmanCryoCrate® LLC, 200 E. First Street, Suites 415/428, Winston-Salem, NC, 27101, USA.
Xu HanCryoCrate® LLC, 200 E. First Street, Suites 415/428, Winston-Salem, NC, 27101, USA.
Shirley A PomponiHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US 1 North, Fort Pierce, FL, 34946, USA. spomponi@fau.edu.
Funding
An Ultra-fast Cooling Device for Vitrification and Cryopreservation of Cells and TissuesR44OD020163 · OD · CRYOCRATE, LLC · PI HAN, XU · 2019 to 2020
$1.9MEstablishment of a First-in-Class Biocompatible and Efficient Cryopreservation Technology Platform for the Next Generation of Cell-Based Therapeutics in Regenerative Medicine and Drug DiscoveryR44OD035392 · OD · CRYOCRATE, LLC · PI HAN, XU · 2024 to 2025
$1.9MInnovation of Biobanking for Cellular Adoptive Immunotherapies Based on a First-in-Class Biocompatible Cryopreservation Technology for T and NK Cells and Their CAR-Engineered ProductsR44CA278579 · NCI · CRYOCRATE, LLC · PI HAN, XU · 2022 to 2023
$1.8MLate-stage Preclinical Development and cGMP Production of a First-in-Class Cornea Cryopreservation Kit Based on FDA FeedbackR44EY033254 · NEI · CRYOCRATE, LLC · PI HAN, XU · 2021 to 2022
$1.5MNovel Biocompatible, High-Throughput Cryopreservation Medium and Method for Enhanced Post-Thaw Migration and Cytotoxicity of NK CellsR33CA302632 · NCI · CRYOCRATE, LLC · PI Xu Han, Xunlei Kang · 2025 to 2026
$609kIn-Situ Cryopreservation Without CryoprotectantsR43OD026279 · OD · CRYOCRATE, LLC · PI HAN, XU · 2018 to 2018
$292kA Novel Cryopreservation Technology for Large Skin Grafts to Facilitate Tissue Banking and Allograft TransplantationsR43AI155070 · NIAID · CRYOCRATE, LLC · PI HAN, XU · 2020 to 2020
$160kAn Ultra-fast Cooling Device for Vitrification and Cryopreservation of Cells and TissuesR43OD020163 · OD · CRYOCRATE, LLC · PI HAN, XU · 2015 to 2015
$153kEPA EPA-R4-SFL-2020-01NCI NIH HHS R33 CA302632NCI NIH HHS R44 CA278579NEI NIH HHS R44 EY033254NIAID NIH HHS R43 AI155070NIH HHS R43 OD020163NIH HHS R43 OD026279NIH HHS R44 OD020163NIH HHS R44 OD035392
6 · The paper itselfAbstract
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