Evidence map›Paper›PMID 39092999›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2024

GelBox: open-source software to improve rigor and reproducibility when analyzing gels and immunoblots.

Utku Gulbulak, Austin G Wellette-Hunsucker, Thomas Kampourakis, Kenneth S Campbell

Abstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. The CabioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Utku GulbulakDivision of Cardiovascular Medicine, University of Kentucky, Lexington, Kentucky, United States.
Austin G Wellette-HunsuckerDivision of Cardiovascular Medicine, University of Kentucky, Lexington, Kentucky, United States.ORCID 0000-0002-4198-2456
Thomas KampourakisDivision of Cardiovascular Medicine, University of Kentucky, Lexington, Kentucky, United States.
Kenneth S CampbellDivision of Cardiovascular Medicine, University of Kentucky, Lexington, Kentucky, United States.ORCID 0000-0001-5615-5958

Funding

Dual filament control of myocardial power and hemodynamicsR01HL148785 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI Kenneth S Campbell, Thomas Kampourakis · 2020 to 2026
$3.2M
Length-dependent activation in human myocardiumR01HL149164 · NHLBI · UNIVERSITY OF KENTUCKY · PI CAMPBELL, KENNETH S, TANNER, BERTRAND C.W. · 2020 to 2023
$2.8M
Biological Basis of Genetic cMyBP-C CardiomyopathiesR01HL173989 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI Kenneth S Campbell, Julian Stelzer · 2024 to 2026
$2.0M
The myosin super-relaxed state and human dilated cardiomyopathyF31HL170558 · NHLBI · UNIVERSITY OF KENTUCKY · PI WELLETTE-HUNSUCKER, AUSTIN · 2024 to 2025
$71k
NHLBI NIH HHS F31 HL170558NHLBI NIH HHS R01 HL148785NHLBI NIH HHS R01 HL149164NHLBI NIH HHS R01 HL173989
6 · The paper itself

Abstract

GelBox is open-source software that was developed with the goal of enhancing rigor, reproducibility, and transparency when analyzing gels and immunoblots. It combines image adjustments (cropping, rotation, brightness, and contrast), background correction, and band-fitting in a single application. Users can also associate each lane in an image with metadata (for example, sample type). GelBox data files integrate the raw data, supplied metadata, image adjustments, and band-level analyses in a single file to improve traceability. GelBox has a user-friendly interface and was developed using MATLAB. The software, installation instructions, and tutorials, are available at https://campbell-muscle-lab.github.io/GelBox/.

Indexed as

SoftwareAnimalsHumansImage Processing, Computer-AssistedReproducibility of Resultsgel electrophoresisimage analysisimmunoblottingrigorsoftware

Identifiers

PMID39092999
PMCPMC11427113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.